dynamic epigenetics

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Unknown (601)
Genomics (260)
Transcriptomics (141)
Proteomics (136)
Methylation profiling (6)
Metabolomics (6)
Other (3)
Genomic (1)

Organisms

Aerococcus urinae NBRC 15544 = CCUG 36881 (122)
Alteromonadales (122)
Candida albicans SC5314 (122)
Canis lupus familiaris (122)
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Clostridioides difficile 630 (122)
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Organisms

Mus musculus (57)
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Repository

biostudies-arrayexpress (231)
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pride (122)
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Disease

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Technology Type

Mass Spectrometry (122)
Shotgun proteomics (61)
Affinity purification coupled with mass spectrometry proteomics (38)
Bottom-up proteomics (22)
Data-dependent acquisition (16)
Gel-based experiment (11)
Mass spectrometry (4)
Chemical cross-linking coupled with mass spectrometry proteomics (4)
Data-independent acquisition (4)
All-ion fragmentation (3)
Mass spectrometry assay (2)
Top-down proteomics (2)
Illumina HumanWG-6 (1)
Illumina HumanMethylation 450K (1)
MSE (1)
SRM/MRM (1)
SWATH MS (1)

Instrument Platform

LTQ Orbitrap (7)
Illumina HiSeq 2000 (4)
Illumina HiSeq 2500 (3)
Illumina Genome Analyzer IIx (2)
Q Exactive (2)
Liquid Chromatography MS - negative - hilic (2)
Illumina HiSeq X (1)
Illumina HiSeq 1500 (1)
NextSeq 550 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 3000 (1)
Illumina HiSeq 4000 (1)
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Xevo G2-S QTof (1)
Diode array detection MS - - reversed-phase-chromatography (1)
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Liquid Chromatography MS - alternating - reverse-phase (1)
Liquid Chromatography MS - alternating - hilic (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2015 (64)
2013 (41)
2016 (39)
2014 (31)
2025 (29)
2023 (26)
2012 (25)
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2011 (16)
2026 (16)
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2008 (4)
2004 (1)

CHEBI ID

CHEBI:17202 (2)
CHEBI:16015 (2)
CHEBI:57947 (1)
CHEBI:5548 (1)
CHEBI:57540 (1)
CHEBI:58223 (1)
CHEBI:73533 (1)
CHEBI:73532 (1)
CHEBI:75947 (1)
CHEBI:13705 (1)
CHEBI:53389 (1)
CHEBI:57427 (1)
CHEBI:57972 (1)
CHEBI:57926 (1)
CHEBI:16367 (1)
CHEBI:5738 (1)
CHEBI:176586 (1)
CHEBI:57305 (1)
CHEBI:167175 (1)
CHEBI:746917 (1)
CHEBI:167938 (1)
CHEBI:24996 (1)
CHEBI:50383 (1)
CHEBI:17665 (1)
CHEBI:17835 (1)
CHEBI:16905 (1)
CHEBI:18095 (1)
CHEBI:86542 (1)
CHEBI:16001 (1)
CHEBI:29042 (1)

Metabolite Name

L-Proline (3)
L-Phenylalanine (3)
Cinobufotalin (2)
Forskolin (2)
Behenic acid (2)
L-Norleucine (2)
Glycine (2)
L-Alanine (2)
Betaine (2)
Adenosine 5'-monophosphate (2)
L-Histidine (2)
Taurine (2)
Niacinamide (2)
L-Arginine (2)
L-Lysine (2)
Citric acid (2)
L-Glutamic acid (2)
Malic acid (2)
Anserine (2)
Sarcosine (2)
Maltotriose (2)
L-Tryptophan (2)
L-Glutamine (2)
Dihydroxyacetone phosphate (2)
D-Proline (2)
L-Serine (2)
Uridine (2)
Creatinine (2)
Creatine (2)
L-Valine (2)

First Public Date

2025 (24)
2024 (19)
2023 (15)
2020 (14)
2019 (14)
2026 (13)
2018 (12)
2013 (8)
2022 (6)
2021 (5)
2015 (5)
2014 (4)
2016 (2)

Modification

N6 (10)
N6-dimethyl-L-lysine (3)
2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

ChIP-seq (68)
Transcription profiling by array (42)
RNA-seq of coding RNA (39)
Methylation profiling by high throughput sequencing (28)
Methylation profiling by array (14)
RNA-seq of non coding RNA (7)
Other (6)
Unknown experiment type (5)
ChIP-chip by tiling array (5)
ChIP-chip by array (5)
Transcription profiling by tiling array (4)
Human - Single-cell sequencing (2)
DNA-seq (2)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Genotyping by array (1)
Bisulfite-seq (1)

Release Date

2025 (82)
2015 (78)
2016 (75)
2022 (62)
2021 (59)
2023 (54)
2020 (53)
2014 (53)
2013 (51)
2018 (46)
2019 (46)
2024 (42)
2012 (37)
2017 (27)
2010 (24)
2011 (22)
2026 (9)
2009 (6)
2008 (5)
2004 (1)

Lab affiliation

Institute of Functional Epigenetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany. (6)
European Institute of Oncology (4)
Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania (3)
Institute of Functional Epigenetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany (3)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (3)
Affiliation of Qiutao Xu: State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Agriculture, Guangxi University, Nanning 530004, China (2)
Department of Biology – Cellular Proteostasis and Mass Spectrometry, University of Konstanz (2)
Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany (2)
Max Planck Institute of Immunobiology and Epigenetics Proteomics Unit Stuebeweg 51 79108 Freiburg, Germany (2)
Proteomics Unit Max Planck Institute of Immunobiology and Epigenetics (2)
2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China. (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University of Munich (TUM) Gregor-Mendel-Strasse 4 85354 Freising Germany (1)
Ben May Department for Cancer Research, The University of Chicago, Chicago, IL, 60637, USA (1)
Blizard Institute, Centre for Genomics and Child Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK (1)
Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK (1)
CSIR-Centre for Cellular and Molceular Biology, Hyderabad, India TIGS-Tata Institute for Genetics and Society ,Bengaluru, India (1)
Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP), Portuguese Oncology Institute of Porto, Porto, Portugal (1)
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Christian Doppler Laboratory for Chemical Epigenetics and Anti-Infectives Lazarettgasse 14, AKH BT 25.3 1090 Vienna, Austria (1)
Cell Biology Program and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA (1)
Center of Excellence on Translational Research in Inflammation and Immunology (CETRII), Department of Microbiology, Chulalongkorn University, Bangkok 10330, Thailand (1)
Centre for Bioinformatics and Computational Biology, University of Stellenbosch, South Africa (1)
Centre for Epigenetics and Department of Biochemistry and Molecular Biology, University of Southern Denmark Campusvej 55 DK-5230 Odense M, Denmark (1)
Centre for Genomic Regulation (CRG) (1)
Chromosome dynamics and genome stability, Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Feodor-Lynen-Strasse 21, 81377 München, Germany (1)
Department of Biochemistry and Biophysics Penn Epigenetics Institute University of Pennsylvania School of Medicine (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biology, Technical University of Darmstadt, Darmstadt, Germany (1)
Department of Cell Biology & Plant Biochemistry, Center for Biochemistry, University of Regensburg, Universitätsstr. 31, D-93053 Regensburg, Germany (1)
Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA 91010 (1)
Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. (1)

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Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related clear cell renal cancer cells (ccRCC) gro...

2022-12-08 | MTBLS5615 | MetaboLights

Multi-Omics analyses reveal dynamic interactions between DNA methylation and transcriptional regulation during black raspberry ripening

We show developmental-series transcriptome, methylome, and metabolome to reveal extensive epigenetic reprogramming during black raspberry (Rubus occidentalis) fruit ripening. Multi-omics integration reveals coordinated anthocyanin accumulation parallels expression of biosynthetic and regulatory gene...

2026-09-28 | MTBLS15819 | MetaboLights

Longitudinal DNA methylation dynamics as a practical indicator in clinical epigenetics.

Not available

S-EPMC8670275 | biostudies-literature

Prohexadione, a plant growth regulator, inhibits histone lysine demethylases and modulates epigenetics.

Not available

S-EPMC5598483 | biostudies-literature

Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis.

Not available

S-EPMC7518697 | biostudies-literature

Epigenetics in depression and gut-brain axis: A molecular crosstalk.

Not available

S-EPMC9794020 | biostudies-literature

An immune and epigenetics-related scoring model and drug candidate prediction for hepatic carcinogenesis via dynamic network biomarker analysis and connectivity mapping.

Not available

S-EPMC10561057 | biostudies-literature

Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [ChIP-Seq]

The leukemogenic fusion protein RUNX1/ETO impairs myeloid differentiation and drives malignant self-renewal. Here we use digital footprinting and ChIP-sequencing to identify the core RUNX1/ETO responsive transcriptional network of t(8;21) cells. We show that the transcriptional programme underlying ...

ORGANISM(S): Homo sapiens

2014-09-24 | E-GEOD-60130 | biostudies-arrayexpress

Epigenetics and Gut Microbiota Crosstalk: A potential Factor in Pathogenesis of Cardiovascular Disorders.

Not available

S-EPMC9774431 | biostudies-literature

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

Our system recapitulates expected characteristics of the well characterized H3.3 histone variant, and show that we gain additional information by using a kinetic approach. Additionaly, our results on the less-studied MacroH2A2 variant revealed differential dynamic profiles of this M-bM-^@M-^\repress...

ORGANISM(S): Mus musculus

2014-08-08 | E-GEOD-57665 | biostudies-arrayexpress

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