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TranscriptomicsTranscription profiling of Saccharomyces cerevisiae eIF4G isoforms to investigate eIF4G deletion transcript abundance
Effect of eIF4G gene deletion on transcript abundance.
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-24 | E-MEXP-2400 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae eIF4G isoforms to investigate eIF4G deletion ribosome occupancy
Effect of eIF4G gene deletion on the ribosome occupancy.
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-24 | E-MEXP-2399 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae eIF4G isoforms to investigate eIF4G homogenic polysome abundance
Effect of expressing a single eIF4G isoform at wild type levels on relative polysome abundance.
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-14 | E-MEXP-2402 | biostudies-arrayexpress
TranscriptomicsDepletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide
Investigation of the effects of genetically depleting eIF4G from yeast cells on global translational efficiencies, using gene expresssion microarrays to measure the abundance of mRNA in polysomes relative to total mRNA for ~5900 genes Three biological replicates were examined (designated projects I,...
ORGANISM(S): Saccharomyces cerevisiae 
2010-12-02 | E-GEOD-25721 | biostudies-arrayexpress
TranscriptomicsLifespan extension via eIF4G inhibition is mediated by post-transcriptional remodeling of stress response gene expression in C. elegans
Reducing protein synthesis slows growth and development but can increase adult lifespan. We demonstrate that knock-down of eukaryotic translation initiation factor 4G (eIF4G), which is down-regulated during starvation, results in differential translation of genes important for growth and longevity i...
ORGANISM(S): Caenorhabditis elegans 
2011-04-16 | E-GEOD-28665 | biostudies-arrayexpress
GenomicsGenome-wide analysis of eIF4G-RNA interaction in CDK12-depleted cells (RIP-Seq)
Genome-wide analysis of eIF4G-RNA interaction in CDK12-depleted cells (RIP-Seq)
PRJNA497254 | ENA
ProteomicsGonatopoulos-Pournatzis _eIF4Gmicroexon_P105_Lumos
A This dataset consists of 24 raw MS files, acquired on Orbitrap Fusion Lumos Tribrid mass spectrometer operated in Data Dependent Acquisition mode. B Mouse samples were generated by Thomas Gonatopoulos-Pournatzis. Proteomics sample preparation and mass spectrometric acquisition was performed by Sh...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-12-04 | MSV000084658 | MassIVE
ProteomicsYeast eIF4G homogenic whole cell oxidative stress LC-MSMS
Translation initiation factor 4G (eIF4G) is an integral component of the eIF4F complex which is key to translation initiation for most eukaryotic mRNAs. Many eIF4G isoforms have been described in diverse eukaryotic organisms but we currently have a poor understanding of their functional roles and wh...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-10-24 | PXD041682 | Pride
Lc-msms Yeast S. cerevisiae Oxidative stress Whole cell 
UnknownSynergistic activation of eIF4A by eIF4B and eIF4G.
Not available
S-EPMC3074137 | biostudies-literature
UnknownScd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins.
Not available
S-EPMC3277450 | biostudies-literature
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