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MetabolomicsPlasma metabolic profile in COPD patients: effects of exercise and endurance training
The study examines plasma metabolic profiles of patients with chronic obstructive pulmonary disease (COPD) to prove whether the disease influences metabolism at rest and after endurance training. This is based on the hypothesis that metabolome levels should reflect impaired skeletal muscle bioenerge...
2017-03-10 | MTBLS249 | MetaboLights
TranscriptomicsTranscription profiling of soleus muscle from lean and obese Zucker rats following exercise training
Endurance exercise training has been shown to decrease whole-body and skeletal muscle insulin resistance and increase glucose tolerance in conditions of both pre-diabetes and overt type 2 diabetes. However, the adaptive responses in skeletal muscle at the molecular and genetic level for these benef...
ORGANISM(S): Rattus norvegicus 
2009-11-16 | E-TABM-213 | biostudies-arrayexpress
TranscriptomicsA transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype
This SuperSeries is composed of the following subset Series: GSE18583: Baseline skeletal muscle gene expression GSE35659: A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype (resting muscle after endurance training) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-35661 | biostudies-arrayexpress
TranscriptomicsImpact of exercise training on endothelial transcriptional profiles in healthy swine: A genome-wide microarray analysis
While the salutary effects of exercise training on conduit artery endothelial cells have been reported in animals and humans with cardiovascular risk factors or disease, whether a healthy endothelium is alterable with exercise training is less certain. The purpose of this study was to evaluate the ...
ORGANISM(S): Sus scrofa 
2011-12-02 | E-GEOD-26663 | biostudies-arrayexpress
TranscriptomicsA transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype (resting muscle after endurance training)
The molecular pathways which are activated and contribute to physiological remodeling of skeletal muscle in response to endurance exercise have not been fully characterized. We previously reported that ~800 gene transcripts are regulated following 6 weeks of supervised endurance training in young se...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-35659 | biostudies-arrayexpress
MetabolomicsDelayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

Exercise is fundamental to healthy aging, yet the degree to which it mitigates age-related molecular changes and how varying physical fitness levels influence the molecular response to exercise with age remain unclear. To address this, we performed transcriptomics, lipidomics, and metabolomics on...

2026-04-09 | MTBLS12824 | MetaboLights
MetabolomicsMetabolomic Profiling of Submaximal Exercise at a Standardised Relative Intensity in Healthy Adults
Ten physically active subjects underwent two cycling exercise trials. In the first, aerobic capacity (VO2max) was determined and the second was a 45 min submaximal exercise test. Urine samples were collected separately the day before (day 1), the day of (day 2), and the day after (day 3) the submaxi...
2017-05-16 | MTBLS306 | MetaboLights
TranscriptomicsThe Heritage (HEalth, RIsk factors, exercise Training And GEnetics) family study
The overall objective of the heritage project is to study the role of the genotype in cardiovascular,metabolic and hormonal responses to aerobic exercise training and the contribution of regular exercise to changes in several cardiovascular disease and diabetes risk factors. The study cohort in this...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-47874 | biostudies-arrayexpress
MetabolomicsPhysiological and Molecular Dissection of Daily Variance in Exercise Capacity
Physical performance relies on the concerted action of myriad responses, many of which are under circadian clock control. Little is known, however, regarding the time-dependent effect on exercise performance at the molecular level. We found that both mice and humans exhibit daytime variance in exerc...
2019-04-07 | MTBLS145 | MetaboLights
MetabolomicsSerum Metabolomic Profiling Reveals Load-Specific Adaptations to Resistance Training
This study deposits the untargeted ¹H-NMR serum metabolomics dataset of a parallel-group, longitudinal resistance training intervention designed to identify load-specific and training-status-specific metabolomic signatures in healthy young men. Seventeen healthy young men (age 24 ± 3 yr; height 173 ...
2026-07-20 | MTBLS15091 | MetaboLights
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