Sort   by:  
 Page size 
ProteomicsMolecular basis of F-actin regulation and sarcomere assembly via myotilin
Sarcomeres, the basic contractile units of striated muscle cells, contain arrays of thin (actin) and thick (myosin) filaments that slide past each other during contraction. The Ig-like domain containing protein myotilin provides structural integrity to Z-discs—the boundaries between adjacent sarcome...
ORGANISM(S): Homo sapiens (Human) 
2021-02-22 | PXD024301 | Pride
Sarcomeric z-disc  f-actin binding  myotilin  α-actinin-2  integrative structural model of f-actin:myotilin  competitive tropomyosin binding  z-disc-assembly regulation Cross-linking mass spectrometry Lc-ms/ms 
ProteomicsPlasma membrane deformation by one-dimensional wetting triggers the formation of a branched F-actin network in endothelial cells
Membrane deformation by one-dimensional (1D) wetting, a physical process driven by the interaction of the plasma membrane with adhesive nanofibers, triggers the formation of filopodium-like plasma membrane protrusions. In these protrusions, F-actin reorganization occurs after membrane deformation. H...
ORGANISM(S): Neisseria meningitidis serogroup C (strain 8013) Homo sapiens (Human) 
2026-05-13 | PXD045648 | Pride
Plasma membrane deformation Branched f-actin network 
GenomicsCoactosin-like F-actin Binding Protein (Cotl1) Plays a Key Role in Adipocyte Differentiation and Obesity
Coactosin-like F-actin Binding Protein (Cotl1) Plays a Key Role in Adipocyte Differentiation and Obesity
PRJNA1244642 | ENA
Proteomicsstudy of actin interactome in Alzheimers disease mouse model
Filamentous actin (F-actin) is one of the major cytoskeleton proteins present in dendritic spines and it is an essential component for defining dendritic spine morphology. We have shown that synaptosomal F-actin levels were significantly decreased in APP/PS1 mice as early as one month of age. The mo...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD050802 | Pride
F-actin loss Alzheimers disease Synapse 
UnknownCaMKIIbeta binding to stable F-actin in vivo regulates F-actin filament stability.
Not available
S-EPMC2572980 | biostudies-literature
UnknownMapping of drebrin binding site on F-actin.
Not available
S-EPMC2866048 | biostudies-literature
UnknownMinimal actin cortices: The αD-helix of ezrin's C-ERMAD governs F-actin binding.
Not available
S-EPMC12796735 | biostudies-literature
UnknownInteractions between the Microtubule Binding Protein EB1 and F-Actin.
Not available
S-EPMC4834876 | biostudies-literature
UnknownStructural basis of the filamin A actin-binding domain interaction with F-actin.
Not available
S-EPMC6173970 | biostudies-literature
ProteomicsStructural basis of MICAL autoinhibition
MICAL proteins play a crucial role in cellular dynamics by binding and disassembling actin filaments, impacting processes like axon guidance, cytokinesis, and cell morphology. Their cellular activity is tightly controlled, as dysregulation can lead to detrimental effects on cellular morphology. Alth...
ORGANISM(S): Homo sapiens (Human) 
2024-10-30 | PXD057312 | Pride
F-actin depolymerization Actin Autoinhibition Rab Mical 
Sort   by:  
 Page size