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MetabolomicsNon-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome
INTRODUCTION: Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring in the first 3 months of life. The most common causes of neonatal cholestasis are infantile hepatitis syndrome (IHS) and biliary atresia (BA). The clinical manifestations of the two diseases are ...
2019-06-25 | MTBLS689 | MetaboLights
ProteomicsIntegrative analysis of proteomic and phosphoproteomic of granulosa cells during follicular atresia in porcine
Ovarian follicular atresia is a natural physiological process, but its mechanism is not fully understood. In this study, a quantitative proteomic and phosphoproteomic of granulosa cell (GC) in the healthy (H), slightly atretic (SA), and atretic follicles (A) of porcine were performed by TMT labeling...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-09-09 | PXD020899 | Pride
Porcine  follicular atresia  granulosa cell  proteomic  phosphoproteomic 
TranscriptomicsGene expression in bovine ovarian follicle granulosa
Granulosa cells mature and die as ovarian follicles enlarge and die (undergo atresia) under the influence of hormones and intrafollicular factors. Later in follicular development, a fluid-filled antrum is formed, a process which is accompanied by a high rate of atresia. These small antral follicles ...
ORGANISM(S): Bos taurus 
2014-05-20 | E-GEOD-39589 | biostudies-arrayexpress
ProteomicsSingle-cell Transcriptomes and Follicular Fluid Proteomics of Ovine Atretic Follicles Reveal the Underlying Mechanisms of Oocyte Degeneration
In mammals, female fertility is determined by the outcome of follicular development (ovulation or atresia). Follicular atresia is a complex physiological process that results in the degeneration of oocytes from the ovary. However, the molecular mechanisms of oocyte degeneration and key protein marke...
ORGANISM(S): Oestrus Ovis 
2024-05-30 | PXD052738 |
TranscriptomicsTranscription profiling of human follicular and transformed follicular lymphoma samples revals genome-wide detection of recurring sites of uniparental disomy
Follicular lymphoma (FL) is the second most common B-cell malignancy representing one quarter of Non-Hodgkin's Lymphomas. Although the disease has a relatively long median survival, the illness follows a fluctuating course of progression punctuated by remissions of variable duration. For as many as ...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-7425 | biostudies-arrayexpress
TranscriptomicsGenome-wide copy number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma
We studied 277 lymphoma samples (198 FL and 79 transformed FL [tFL]) using a single-nucleotide polymorphism array to identify the secondary chromosomal abnormalities that drive the development of FL and its transformation to diffuse large B-cell lymphoma. Affymetrix 250K NspI SNP arrays were perform...
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-67385 | biostudies-arrayexpress
TranscriptomicsIdentification of discriminant genes and gene networks involved in pig ovarian follicular atresia
Folliculogenesis corresponds to the development of follicles leading to either ovulation or degeneration (a process called atresia). Even if atresia involves an apoptosis process, this mechanism is not well understood. The objective of this experiment was : 1) to analyse gene expression in pig granu...
ORGANISM(S): Sus scrofa 
2010-06-24 | E-GEOD-7635 | biostudies-arrayexpress
ProteomicsA Tale of Two Follicles: Proteomic Clues to Oocyte Success and Failure
Women are born with thousands of follicles in their ovaries but less than 1% will produce a mature oocyte. What distinguishes the 99% of ovarian follicles destined for demise from the rare 1% that succeed? Here, we leveraged a unique clinical opportunity, paired follicular fluid samples from small a...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD063187 | Pride
Metabolism Atresia Fertility preservation Oocyte maturation Follicular fluid 
ProteomicsProteomics of normal and atretic follicles in geese
Follicular atresia is an important factor affecting reproductive performance. In birds, less than 5% of follicles could complete their development process and mature ovulation, while the other 95% become atretic follicles and eventually degraded3. Yangzhou geese are famous for their high egg product...
ORGANISM(S): Anser Canagica 
2021-09-29 | PXD028836 |
Proteomicsgoose follicular fluid exosomes proteomic
Proteomic analysis of follicular fluid exosomes derived from SYFs and ASYFs in geese
ORGANISM(S): Anser cygnoides domesticus 
2024-08-10 | PXD049994 | Pride
Goose follicular fluid exosomes proteomic 
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