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To decipher the beneficial effects of Polyphenols on health, healthy volunteers were randomized into two groups and were submitted to either a red grape polyphenol rich extract supplemented diet (PP) or a placebo diet (PCB) during 8 weeks. Then they were submitted to a fructose load (3g/kg Fat Free ...
ORGANISM(S): Homo sapiens 
To identify protein targets of fructose, we performed a compound-centric chemical proteomics (CCCP) experiment on podocytes with P-fructose. Briefly, podocytes were incubated with P-fructose, and the cellular proteins that directly bind to fructose were covalently crosslinked to P-fructose by UV irr...
ORGANISM(S): Homo sapiens (Human) 
2026-06-05 | PXD047310 | Pride
Transcriptional profiling of Haloferax mediterranei DF50 and M-NM-^TdeoR2 with induction by fructose comparing with the strains without this induction. Goal was to explore the effect of induction by fructose on Haloferax mediterranei. Total RNA from the Haloferax mediterranei DF50 and M-NM-^TdeoR2 w...
ORGANISM(S): Haloferax mediterranei 
Whole genome gene expression analysis was examined with Ralstonia eutropha strain H16 cultures grown in PHB production medium (recipe per Peoples and Sinskey, 1989) containing fructose or trioleate as the main carbon source. The goal of this analysis was to determine the identity of the triacylglyc...
ORGANISM(S): Cupriavidus necator 
After identifying Tom22 as a direct target of fructose, we sought to map the potential sites that fructose binds to Tom22. We analyzed trypsin-digested peptides of P-fructose-labeled recombinant Tom22 by high-resolution mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2026-06-05 | PXD047275 | Pride
Hepatic stellate cells are involved in the development of hepatic fibrosis. We here perform transcriptional profiling of hepatic stellate cells (HSCs) isolated from Western diet/high fructose-fed C57BL6/J mice, carbon tretrachloride (CCl4)-treated C57BL6/J mice, and of murine HSCs differentiated in ...
ORGANISM(S): Mus musculus 
Transcriptional profiling of A. nidulans comparing Xylose and Fructose grown on Wild type strain. The main objective was to identifiy genes related to Xylose transport. The experiment was further validated by real-time PCR. Three-condition experiment : A. nidulans strains grown during 16 h on fructo...
ORGANISM(S): Aspergillus nidulans FGSC A4 
Harmful effects of high fructose intake on health have been widely reported in epidemiological and laboratory studies. Although it has been reported that fructose promotes cancer development and progression, little is known about the underlying molecular mechanisms. Here, we found that fructose trig...
ORGANISM(S): Homo sapiens (Human) 
2020-11-09 | PXD021035 | Pride
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