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Conservation of the extended substrate specificity profiles among homologous granzymes across species

Granzymes are a family of structurally related serine proteases involved in immunity. To date four out of five human granzymes have been assigned orthologues in mice; however for granzyme H, no clear murine orthologue has been suggested and its role in cytotoxicity remains controversial. In this stu...

ORGANISM(S): Mus musculus (Mouse)

2013-11-27 | PXD000152 | Pride