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ProteomicsA fast, high-sensitivity 96-well plate based MICROFASP method for processing low microgram proteomics sample within 1.5 hours
We report a fast, high-sensitivity MICROFASP method that capable of completing sample preparation in less than 1.5 h which improved the throughput over 13 times compared to the previous reports. In this method, protein digestion time was dramatically shortened from 17 h to 20 min in the limited reac...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-05-07 | PXD053720 | Pride
Fast sample preparation  proteomics analysis  high-sensitivity  high-throughput 
ProteomicsTwo-step peptide solubilization increases coverage in high-sensitivity nanoHILIC/MS/MS-based proteomics
Nanoscale hydrophilic-interaction chromatography coupled with tandem mass spectrometry (nanoHILIC/MS/MS) is a promising alternative to reversed-phase liquid chromatography (RPLC) for proteomics, but its application is limited by the poor solubility of peptides in organic solvent-rich sample solution...
ORGANISM(S): Homo Sapiens (human) Bos Taurus 
2025-05-08 | PXD059304 | JPOST Repository
GenomicsHigh origin firing capacity leads to ATR inhibitor sensitivity via increased replication catastrophe
High origin firing capacity leads to ATR inhibitor sensitivity via increased replication catastrophe
PRJEB85428 | ENA
GenomicsHigh glucose associated YTHDC1 lactaylation reduces the sensitivity of bladder cancer to enfortumab vedotin therapy
High glucose associated YTHDC1 lactaylation reduces the sensitivity of bladder cancer to enfortumab vedotin therapy
PRJNA1234198 | ENA
GenomicsNULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing
NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing
PRJNA1009393 | ENA
GenomicsOseltamivir enhances 5-FU sensitivity in esophageal squamous carcinoma with high SPNS1
Oseltamivir enhances 5-FU sensitivity in esophageal squamous carcinoma with high SPNS1
PRJNA1026861 | ENA
ProteomicsMetallothionein immunohistochemistry has high sensitivity and specificity for detection of Wilson disease
Diagnosis of Wilson disease (WD) can be difficult because of its protean clinical presentation, but early diagnosis is important because effective treatment is available and can prevent disease progression. Using quantitative proteomics, we characterized proteins that are differentially expressed in...
ORGANISM(S): Homo sapiens (Human) 
2023-04-18 | PXD029069 | Pride
Quantitative proteomics Immunohistochemistry Liver Wilson disease Mt1g Sensitivity Metallothionein-1g Specificity 
GenomicsMultitissue Single-Cell Analysis Reveals Differential Tissue, Cellular, and Molecular Sensitivity between Fructose and High fat high sucrose Diets
Multitissue Single-Cell Analysis Reveals Differential Tissue, Cellular, and Molecular Sensitivity between Fructose and High fat high sucrose Diets
PRJNA860948 | ENA
GenomicsSLFN11 captures cancer-immunity interactions associated with platinum sensitivity in high-grade serous ovarian cancer
SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in high-grade serous ovarian cancer
PRJNA745556 | ENA
ProteomicsAn improved nanoflow RPLC-CZE-MS/MS system with high peak capacity and sensitivity for nanogram bottom-up proteomics
Novel mass spectrometry (MS)-based proteomic tools with extremely high sensitivity and high peak capacity are required for comprehensive characterization of protein molecules in mass-limited proteome samples. We previously reported a nanoflow RPLC-CZE-MS/MS (nanoRPLC-CZE-MS/MS) system for deep botto...
ORGANISM(S): Homo sapiens (Human) 
2019-10-23 | PXD014392 | Pride
Human cells Nanorplc-cze-ms/ms Bottom-up proteomics Nanograms 
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