inhibitory receptors

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UNIPROT ID/AC

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Metabolite Name

Methyl Indole-3-Acetate (2)
Longicamphenylone (2)
13E-Docosenamide (2)
Indole-3-Carboxaldehyde (2)
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Betaine (2)
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L-Ornithine (2)
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School of Life Sciences, University of Dundee, Dundee, UK (2)
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Center for Tumor Biology and Immunology (ZTI), Philipps University, Hans-Meerwein-Strasse 3, 35043 Marburg, Germany (1)
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Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic (1)
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Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, Pozzuoli, Naples, Italy (1)
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Laboratory of Molecular Oncology1, Institut de recherches cliniques de Montréal (IRCM), Montréal, Québec, Canada H2W1R7; Department of Medicine2, McGill University, Montréal, Québec, Canada H3G 1Y6 (1)
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Keyword

Patients with mCRC who failed 2nd therapy or more (1)
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protozoa (3)

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Transcription profiling by array (221)
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APEX protemics of the inhibitory receptors CLTA-4, LAG-3 and TIM-3

APEX proteomics data of the vesicular proteome of the T cell inhibitory receptors CTLA-4, LAG3 and TIM3 as described in https://biorxiv.org/cgi/content/short/2023.07.21.550019v1

ORGANISM(S): Mus musculus (Mouse)

2023-10-26 | PXD044064 | Pride

Mouse T cell Apex Inhibitory receptor

CXCR3+ Treg cells suppress Th1-immune responses through expression of the co-inhibitory receptors CD85k and Lag-3

CD4+Foxp3+ Treg cells are essential for maintaining self-tolerance and preventing excessive immune responses. In the context of Th1 immune responses, co-expression of the Th1 transcription factor T-bet with Foxp3 is essential for Treg cells to control Th1 responses. T-bet-dependent expression of CXC...

ORGANISM(S): Mus musculus

2018-06-30 | E-MTAB-6156 | biostudies-arrayexpress

CMV infection induces a rapid and sustained change in the expression of Natural Killer Cell Receptors on CD8+ T Cells

The CD8+ T cell compartment of human cytomegalovirus (CMV) seropositive individuals characteristically contains a high proportion of cells that expresses Natural Killer Cell Receptors (NKR) which may contribute to the surveillance of virus-infected cells. To test if this enhanced expression is a dir...

ORGANISM(S): Homo sapiens

2008-08-28 | E-GEOD-12589 | biostudies-arrayexpress

IL-27 and TCR stimulation promote T cell expression of multiple inhibitory receptors

PRJNA511005 | ENA

Complex regulation of Gephyrin splicing is a determinant of inhibitory postsynaptic diversity

Gephyrin (GPHN) regulates the clustering of postsynaptic components at inhibitory synapses and is involved in pathophysiology of neuropsychiatric disorders. Here, we uncover an extensive diversity of GPHN transcripts that are tightly controlled by splicing during mouse and human brain development. P...

ORGANISM(S): Mus musculus (Mouse)

2022-06-28 | PXD033751 | Pride

Splice variants Gephyrin Inhibitory synapses

TLR 4 Signaling Inhibitory Pathway Induced by Green Tea Polyphenol Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor

Epigallocatechin-3-gallate (EGCG), a major active polyphenol of green tea, has been shown to downregulate inflammatory responses in macrophages; however, the underlying mechanism has not been understood. Recently, we identified the 67-kDa laminin receptor (67LR) as a cell-surface EGCG receptor that ...

ORGANISM(S): Mus musculus

2010-04-20 | E-GEOD-21320 | biostudies-arrayexpress

CXCR3+ Treg cells suppress Th1-immune responses through expression of the co-inhibitory receptors CD85k and Lag-3

PRJEB23252 | ENA

A chemical genetic approach identifies piperazine antipsychotics as promoters of CNS neurite growth on inhibitory substrates.

Injury to the central nervous system (CNS) may result in lifelong loss of function due, in part, to the regenerative failure of CNS neurons. Major barriers to regeneration faced by injured CNS neurons include inhibitory proteins derived from myelin and the astroglial scar. Previously, we described...

ORGANISM(S): Homo sapiens

2012-04-29 | E-GEOD-34331 | biostudies-arrayexpress

Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer

PRJNA1403544 | ENA

IL-27 and TCR stimulation promote T cell expression of multiple inhibitory receptors

Inhibitory receptors (IR) are a diverse group of cell surface molecules that modulate T cell activation, but there are gaps in our knowledge of the cell extrinsic factors that regulate their expression. The present study found that in vivo overexpression of IL-27 led to increased T cell expression o...

ORGANISM(S): Mus musculus

2019-01-17 | GSE124222 | GEO

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