Sort   by:  
 Page size 
ProteomicsEvaluation of the technical reproducibility of serum proteome sample preparation methods to support clinical proteomics applications
Evaluation of the efficiency and reproducibility of sample prepration methods using iST-BCT kit from PreOmics or SMART Trypsin Kit (Thermo Fisher) with in-house Rapigest protocol in human serum samples prior to mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2025-04-07 | PXD051002 | Pride
Serum  proteomics  biomarker  mass spectrometry  rapigest sf  ist-bct  smart digest trypsin 
ProteomicsImpact of variations in standard operating procedure on plasma proteome recovery
Advancements in mass spectrometry and complementary technologies now enable comprehensive and high-resolution plasma proteomics. Plasma is a key biofluid for clinical research, harboring potential disease informative biomarkers. Commercial sources of non-diseased, healthy donor plasma samples are of...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD069212 | Pride
Mass spectrometry Clinical proteomics Biofluids Data-independent acquisition 
ProteomicsImpact of variations in standard operating procedure on plasma proteome recovery
Advancements in mass spectrometry and complementary technologies now enable comprehensive and high-resolution plasma proteomics. Plasma is a key biofluid for clinical research, harboring potential disease informative biomarkers. Commercial sources of non-diseased, healthy donor plasma samples are of...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD069325 | Pride
Mass spectrometry Clinical proteomics Biofluids Data-independent acquisition 
UnknownEvaluation of Serum Proteome Sample Preparation Methods to Support Clinical Proteomics Applications.
Not available
S-EPMC11546599 | biostudies-literature
ProteomicsProteomics Data of "Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema" Study
Background: Chronic hand eczema (CHE) is a debilitating skin condition characterized by pain, itch, and chronic inflammation, with a complex multifactorial origin. Its diverse presentations, including overlapping traits of atopic dermatitis, contact dermatitis, and psoriasis, make diagnosis and trea...
ORGANISM(S): Homo sapiens (Human) 
2026-02-26 | PXD059218 | Pride
ProteomicsTechnical evaluation of human plasma proteomics methods
In our study, seven plasma proteomics methods were evaluated including five MS-based protocols (Neat (Untreated), TOP14 depletion (Thermo Scientific), Enrich (PreOmics, part of Bruker now), PCA-N (Mann’s protocol + ref) and Proteograph XT (Seer)) and two antibody-based ones (Olink Target Inflammatio...
ORGANISM(S): Homo sapiens (Human) 
2025-12-16 | PXD070072 | Pride
Plasma Depletion Affinity-based proteomics Enrichment Mass spectrometry Proteomics 
ProteomicsMulti-center longitudinal quality assessment of MS-based proteomics in plasma and serum
Advancing MS-based proteomics towards clinical applications evolves around developing standardized start-to-finish and fit-for-purpose workflows for clinical specimens. Steps along the method design involve the determination and optimization of several bioanalytical parameters such as selectivity, s...
ORGANISM(S): Homo sapiens (Human) 
2025-02-14 | PXD054073 | Pride
Plasma Serum Round robin study R package mpwr Lc-ms/ms 
ProteomicsCovalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C
The discovery of KRAS G12C inactive state inhibitors represents a significant advancement in the field of precision oncology. While inactive state inhibition shows promise in patients, SWII-binding inhibitors targeting both inactive and active states remain an underdeveloped therapeutic modality. H...
ORGANISM(S): Homo sapiens (Human) 
2025-11-04 | PXD062227 | Pride
ProteomicsRhodnius prolixus hemolymph proteome
This project aims to investigate the immuno-physiology of the Chagas disease vector Rhodnius prolixus, by analysing the effect of blood ingestion and Trypanosoma cruzi colonisation of its digestive tract on the modulation of protein expression in the hemolymph.
ORGANISM(S): Rhodnius prolixus (Triatomid bug) 
2022-04-27 | PXD032787 | Pride
Hemolymph Chagas disease Triatomines Insect innate immunity 
ProteomicsFrontiers in Plasma Proteome Profiling Platforms: Innovations and Applications.
Biomarkers play a crucial role in advancing precision medicine by enabling more targeted and individualized approaches to diagnosis and treatment. Various biofluids, including serum, plasma, cerebrospinal fluid (CSF), saliva, tears, pancreatic cyst fluids, and urine, have been identified as rich sou...
ORGANISM(S): Homo sapiens (Human) 
2024-07-03 | PXD050425 | Pride
Biomarker Sp100 instrument Biofluids proteome profiling Preomics-ist Seer proteograph Timstofpro2 Secretome Plasma proteome 
Sort   by:  
 Page size