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Unknown<i>JCHAIN</i>: A Prognostic Marker Based on Pan-Cancer Analysis to Inhibit Breast Cancer Progression.
Not available
S-EPMC12469470 | biostudies-literature
GenomicsRNAseq analysis of bone marrow plasma cells from Taciflox/flox and Jchain-CreERT2 Taciflox/flox mice
RNAseq analysis of bone marrow plasma cells from Taciflox/flox and Jchain-CreERT2 Taciflox/flox mice
PRJNA1310300 | ENA
UnknownComprehensive Analysis of JCHAIN as a Potential Prognostic Factor for Breast Cancer and an Indicator for Tumor Microenvironment.
Not available
S-EPMC12561060 | biostudies-literature
TranscriptomicsRNAseq analysis of bone marrow plasma cells from Taciflox/flox and Jchain-CreERT2;Taciflox/flox mice
Durable neutralizing antibodies are essential for vaccine-induced protection and are continuously secreted by bone marrow long-lived plasma cells (LLPCs). The longevity of these cells largely dictates the duration of vaccine-induced immune protection. We perfomred conditional deletion of TACI in PCs...
ORGANISM(S): Mus musculus 
2026-06-10 | GSE306258 | GEO
UnknownJchain-Diphtheria Toxin Receptor Mice Allow for Diphtheria Toxin-Mediated Depletion of Antibody-Secreting Cells and Analysis of Differentiation Kinetics.
Not available
S-EPMC11100621 | biostudies-literature
Unknown<i>Jchain</i>-diphtheria toxin receptor mice allow for depletion of antibody-secreting cells and analysis of differentiation kinetics.
Not available
S-EPMC12666722 | biostudies-literature
UnknownBroadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain.
Not available
S-EPMC9969645 | biostudies-literature
UnknownAssociation of chaperone-mediated autophagy with the mechanisms of vascular calcification in diabetic nephropathy.
Not available
S-EPMC12329838 | biostudies-literature
ProteomicsIdentification of TFG- and autophagy-regulated proteins and glycerophospholipids in B cells shows a role for TFG in metabolism
Autophagy supervises proteostasis and survival of plasma cells. TFG (Trk-fused gene) promotes autophagosome-lysosome flux in murine CH12 B cells, as well as their survival. Moreover, TFG is abundant in plasma cells. Hence, quantitative proteomics of CH12tfgKO and WT B cells in combination with lyso...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-27 | PXD039180 | Pride
Autophagy  autophagy flux  lysosome  b cell  endoplasmic reticulum stress  ribosome  immunoglobulin  plasma cell  jchain  trk-fused gene  phosphatidylglycerol 
UnknownThe immunoglobulin J chain is an evolutionarily co-opted chemokine.
Not available
S-EPMC10801876 | biostudies-literature
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