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MetabolomicsZinc oxide nanoparticles supplementation improve the quality and lipid profiles of boar frozen semen

Oxidative stress frequently causes a reduction in the quality of frozen-thawed sperm. Zinc oxide nanoparticles (ZnONPs) has an antioxidant protective effect on frozen semen of animals such as goats, camels and buffaloes. However, it is not clear whether ZnONPs can improve the quality and lipid co...

2026-05-05 | MTBLS12892 | MetaboLights
MetabolomicsPolystyrene nanoparticles promote endometrial cancer development through the ACSS2-mediated reprogramming of arachidonic acid metabolism

Microplastics and nanoplastics are commonly found in our everyday environments. So far, microplastics and nanoplastics have been detected in various tissues and bodily fluids, including hair, sputum, digestive tissue, lungs, blood, and placental tissue. Although some studies indicate that micropl...

2026-02-05 | MTBLS13850 | MetaboLights
GenomicsInvestigation of the effects of Dsi-RNA-loaded lipid nanoparticles on whole liver tissue
Investigation of the effects of Dsi-RNA-loaded lipid nanoparticles on whole liver tissue
PRJNA879207 | ENA
TranscriptomicsGlobal genetic impact of surface-modified gold nanoparticles on two model human cell lines
Gold nanoparticles (Au NPs) are uniquely suited for various biomedical applications due to the combination of their optical properties with their easily functionalized surfaces. The Au NP surface can be tailored to improve biocompatibility while also attaching targeting ligands or drugs. However, in...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-56432 | biostudies-arrayexpress
ProteomicsLipid nanoparticles improves ex vivo gene editing of human hematopoietic cells
Ex-vivo gene editing in T cells and hematopoietic stem/progenitor cells (HSPCs) holds promise for treating diseases by non-homologous end joining (NHEJ) gene disruption or homology-driven repair (HDR) gene correction. Gene editing encompasses delivery of nucleases by electroporation and, when aiming...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037529 | Pride
Hunan Nanoparticles Hematopoietic cells 
ProteomicsNanoparticles and photochemistry for Native-like transmembrane protein footprinting
Mass spectrometry based footprinting can probe higher order structure of proteins. We bond photocatalytic nanoparticles to a lipid bilayer that, upon laser irradiation, produce high local concentrations of radicals that penetrate the lipid layer made permeable by a simultaneous laser-initiated PB re...
ORGANISM(S): Homo sapiens (Human) 
2021-09-26 | PXD027819 | Pride
Footprinting Membrane protein 
TranscriptomicsPulmonary miRNA expression in C57BL/6 mice intratracheally instilled with Printex 90 carbon black nanoparticles
This SuperSeries is composed of the following subset Series: GSE36170: Pulmonary miRNA expression in C57BL/6 Bom Tac mice (dams) intratracheally instilled with Printex 90 carbon black nanoparticles GSE36171: Pulmonary miRNA expression in C57BL/6 non-pregnant female mice intratracheally instilled wit...
ORGANISM(S): Mus musculus 
2012-04-01 | E-GEOD-36199 | biostudies-arrayexpress
GenomicsEpigenetic metabolite lipid nanoparticles alleviate venous thrombosis via bone marrow reprogramming
Epigenetic metabolite lipid nanoparticles alleviate venous thrombosis via bone marrow reprogramming
PRJNA1195983 | ENA
GenomicsLipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity
Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity
PRJNA1138765 | ENA
ProteomicsMicroRNA137-loaded lipid nanoparticles regulate synaptic proteins in the prefrontal cortex
Genome-wide association studies indicate allele variants in MIR137, the host gene of microRNA-137 (miR137), confer an increased risk of schizophrenia (SCZ). Expression of miR137 and its targets, many of which regulate synaptic functioning, are also associated with an increased risk of SCZ. As a resu...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-05 | PXD041648 | Pride
Schizophrenia Isobaric labeling Prefrontal cortex Mass spectrometry Lipid nanoparticle Personalized medicine Microrna Quantitative proteomics Synaptic proteins 
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