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Suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA) are both histone deacetylases inhibitor (HDACi), and are able to attenuate the activation of hepatic stelllate cells. To explore the underlying molecular mechanisms, we performed gene expression profile analyses of human hepatic stellate...
ORGANISM(S): Homo sapiens 
Suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA ) are both histone deacetylases inhibitor (HDACi), and are able to attenuate the activation of hepatic stelllate cells. To explore the underlying molecular mechanisms, we performed miRNA expression profile analyses of human hepatic stella...
ORGANISM(S): Homo sapiens 
Genome-wide analysis of human monocytes cultured on wt- LX2 or CD44 ko LX2
Klebsiella pneumoniae strain:LX2 Genome sequencing and assembly
BNC2 cistrome and epigenome in myofibroblastic LX2 cells
Effect of DBP in LO2 and LX2 cells
The human hepatic stellate cell line LX2 was treated with 8 Gy X-ray irradiation and/or 2ng/ml recombinant human TGF-β1. The iTRAQ-based high throughput quantitative proteomic approach was used to obtain a comprehensive view of the protein ensembles affected by irradiation and/or TGF-β1 treatment on...
ORGANISM(S): Homo sapiens (Human) 
2018-12-04 | PXD011242 | Pride
Transcriptomic analysis of BNC2 regulated genes in LX2 cells
Effect of ginkgetin on gene expression of LX2 hepatic stellate cells
The goal of this study was to use Rapid Immunoprecipitation Mass spectrometry of Endogenous protein (RIME) assays (Mohammed et al., 2016) to identify transcriptional regulatory partners of the transcription factor BNC2 in LX2 cells. Protein complexes were immune-precipitated with an anti-BNC2 antibo...
ORGANISM(S): Homo sapiens (Human) 
2022-08-05 | PXD003624 | Pride
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