microglia/macrophages

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Unknown (2045)
Genomics (598)
Transcriptomics (495)
Proteomics (33)
Other (11)
Methylation profiling (3)
Metabolomics (3)

Organisms

Mus musculus (388)
Homo sapiens (134)
Aerococcus urinae NBRC 15544 = CCUG 36881 (27)
Allexis (27)
Canis lupus familiaris (27)
Carya cathayensis (27)
Clostridioides difficile 630 (27)
Cyanophora paradoxa (27)
Ensifer adhaerens (27)
Enterococcus faecalis (27)
Globicatella sanguinis (27)
Histomonas meleagridis (27)
Human immunodeficiency virus 1 (27)
Listeria monocytogenes (27)
Marchantia polymorpha (27)
Methylohalobius crimeensis 10Ki (27)
Mus musculus (27)
Mycobacterium tuberculosis (27)
Ophrys garganica (27)
Ophrys sphegodes (27)
Physcomitrium patens (27)
Pseudomonas aeruginosa SJTD-1 (27)
Pseudomonas putida KT2440 (27)
Rattus norvegicus (27)
Rhizobium sp. Leaf68 (27)
Rattus norvegicus (12)
Macaca mulatta (10)
Danio rerio (9)
Ovis aries (6)
mixed sample (1)

Organisms

Mus musculus (355)
Homo sapiens (116)
Macaca mulatta (10)
Rattus norvegicus (8)
Danio rerio (7)
Ovis aries (3)
Sus scrofa (1)
mouse gut metagenome (1)
unidentified (1)

Repository

ENA (555)
geo (481)
biostudies-arrayexpress (66)
pride (27)
MassIVE (4)
EGA (3)
ExpressionAtlas (2)
MetaboLights (2)
GNPS (1)
jPOST (1)
NODE (1)

Tissue

Brain (15)
Macrophage (6)
Microglial cell (6)
Blood (2)
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Cell culture (2)
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Pluripotent stem cell (2)
T cell (2)
Femur (1)
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Tibia (1)
Umbilical cord (1)
Vitreous humor (1)

Disease

Glioblastoma (2)
Niemann-Pick disease (2)
Glioblastoma multiforme (1)
Normal (1)
HIV-associated dementia (1)
Amyotrophic lateral sclerosis (1)
Brain cancer (1)
Brain glioblastoma multiforme (1)
Disease free (1)
Inflammation (1)
Multiple sclerosis (1)

Technology Type

Mass Spectrometry (27)
Shotgun proteomics (14)
Bottom-up proteomics (6)
Affinity purification coupled with mass spectrometry proteomics (5)
Data-independent acquisition (3)
Data-dependent acquisition (2)
Mass spectrometry (1)
Mass spectrometry assay (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (4)
Illumina HiSeq 2500 (3)
Illumina HiSeq 4000 (2)
NextSeq 500 (2)
6410 Triple Quadrupole LC/MS (2)
6545 Q-TOF LC/MS (2)
Q Exactive Plus (2)
Liquid Chromatography MS - positive - reverse phase (2)
Liquid Chromatography MS - negative - reverse phase (2)
BD Rhapsody (1)
NextSeq 2000 (1)
NextSeq 550 (1)
Q Exactive (1)

Publication Date

2026 (92)
2025 (78)
2024 (77)
2020 (43)
2023 (42)
2021 (37)
2022 (36)
2018 (31)
2019 (25)
2016 (21)
2017 (21)
2015 (20)
2014 (18)
2013 (12)
2011 (9)
2012 (7)
2007 (5)
2010 (4)
2008 (2)
2004 (2)
2009 (1)

Metabolite Name

Adefovir Dipivoxil (Preveon, Hepsera) (1)
Indomethacin (Indocid, Indocin) (1)
MLS001148580-01!6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE (1)
Toremifene Citrate (Fareston, Acapodene) (1)
[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1)
(+)-Cycloolivil 4'-O-¦Â-D-glucopyranoside (1)
(+)-Fasciculic acid B (1)
(+)-Lyoniresinol 2¦Á-O-¦Â-D-glucopyranoside (1)
(-)-Hydroxymatairesinol (1)
(-)-Medicocarpin;Medicarpin 3-O-glucoside (1)
(-)-Syringaresinol-4-O-¦Â-D-glucopyranoside (1)
(-)-threo-Iso(homo)2-citrate;(-)-threo-1-Hydroxy-1,2,5-pentanetricarboxylic acid;1-Hydroxypentane-1,2,5-tricarboxylate;threo-(Homo)2-isocitrate (1)
(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy- (1)
(1,3-Dihydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl) 3,4-dimethoxybenzoate (1)
(10-Hydroxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) (Z)-2-methylbut-2-enoate (1)
(11E)-11-Octadecenoic acid (1R,2S)-2-[[(Z)-9-hexadecenoyl]oxy]-1-methylpropyl ester (1)
(12Z)-9,10,11,14,15,16,17,18,19,20,21,22-Dodecahydro-5,8-ethenobenzo[20]annulene-2,4,6,24-tetrol (1)
(13S)-13-Ethoxy-1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine (1)
(14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione (1)
(14S)-9,20,21,25-Tetramethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-1(30),3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,28,31-tetradecaen-2-one (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,33,37-pentahydroxy-18,36-dimethyl-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-9,13,15-trione (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,33,37-hexahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate (1)
(1E)-4-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodec-1-en-3-one (1)
(1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylate (1)
(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol (1)
(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-1,2,3,4,5,6,7,11b-octahydrobenzo[a]quinolizin-5-ium-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium-6-ol (1)
(1R,10R)-5-amino-14-oxido-14-oxo-13,15,18-trioxa-2,4,6,9-tetraza-14lambda5-phosphatetracyclo[8.8.0.03,8.012,17]octadeca-3(8),4-diene-7,11-dione (1)
(1R,14R,24S)-24-Methoxy-5,7,19,21,25-pentaoxa-13-azahexacyclo[12.11.0.02,10.04,8.015,23.018,22]pentacosa-2,4(8),9,15(23),16,18(22)-hexaene (1)
(1R,2'S,3'aS,12S,14S)-2',12-dimethylspiro[13-oxa-2,10,17-triazatetracyclo[10.3.2.02,11.04,9]heptadeca-4,6,8,10-tetraene-14,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,16-trione (1)
(1R,2R,5R,8R,9S,10R,11S)-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)

First Public Date

2025 (89)
2026 (87)
2024 (75)
2023 (48)
2020 (47)
2021 (40)
2022 (39)
2018 (31)
2017 (29)
2019 (24)
2014 (21)
2016 (11)
2015 (11)
2013 (3)

Study type

Transcription profiling by array (38)
RNA-seq of coding RNA (15)
RNA-seq of coding RNA from single cells (6)
ChIP-seq (3)
Cell line - Single-cell sequencing (1)
Animal - Single-cell sequencing (1)
Comparative genomic hybridization by array (1)
Proteomic profiling by array (1)

Release Date

2022 (248)
2023 (231)
2021 (218)
2020 (208)
2024 (201)
2025 (194)
2019 (131)
2018 (130)
2017 (124)
2016 (95)
2015 (81)
2014 (54)
2012 (38)
2013 (37)
2011 (30)
2026 (30)
2010 (15)
2008 (13)
2009 (10)
2007 (9)
2006 (4)
2005 (3)
2001 (2)
2004 (1)
2003 (1)
2000 (1)
1999 (1)
1998 (1)

Lab affiliation

DZNE Munich, Neuroproteomics, Feodor-Lynen Str. 17, 81377 Munich, Germany (2)
Carolin Daniel Helmholtz Zentrum München German Research Center for Environmental Health Institute of Diabetes Research Young Investigator Group Immune Tolerance in Diabetes Ingolstädter Landstrasse 1 85764 München-Neuherberg (1)
Charite Ophthalmology / MDC Cellular Neuroscience (1)
DZNE - German Center for Neurodegenerative Diseases Munich, Neuroproteomics, Feodor-Lynen Str. 17, D-81377 Munich, Germany (1)
Department of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Chemistry, The Scripps Research Institute (1)
Department of Neurology, University of North Carolina, Chapel Hill, NC, USA (1)
Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada (1)
Dept. of Anatomy and Neurobiology, Dept. of Pharmacology, Physiology and Biophysics and Dept. of Neurology, Boston University School of Medicine, Boston, MA (1)
Evandro Chagas National Institute of Infectious Diseases (INI) - Oswaldo Cruz Foundation (FIOCRUZ) (1)
German Center for Neurodegenerative Diseases Munich, Neuroproteomics, Feodor-Lynen Str. 17, D-81377 Munich, Germany (1)
Gladstone Institutes (1)
Hotchkiss Brain Institute and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada Departments of Biochemistry and Molecular Biology, and Physiology and Pharmacology, and McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Canada (1)
Immune monitoring lab, Department of Immunology Leiden University Medical Center (LUMC) The Netherlands (1)
Institute of Human Genetics, Jena University Hospital, Friedrich Schiller University, Am Klinikum1, 07747 Jena, Germany (1)
Institute of Innate Immunity, University of Bonn (1)
Kirby Neurobiology Center, Boston Children's Hospital, Boston MA (1)
Laboratory of Neural Development and Regeneration, CIBIO Department - University of Trento Via Sommarive 9, 38123 Trento, ITALY Centre for Medical Sciences - CISMed University of Trento Via S. Maria Maddalena 1, 38122 Trento, Italy (1)
MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China (1)
Neuroproteomics DZNE Munich Feodor-Lynen-Str. 17 81377 Munich Germany (1)
Nuffield Department of Medicine, University of Oxford (1)
Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore 138648, Singapore (1)
The Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria (1)
UK Dementia Research Institute at University of Edinburgh, University of Edinburgh, Edinburgh bioQuarter, Chancellor’s Building, 49 Little France Crescent, Edinburgh, EH16 4SB UK (1)
University of Calgary, Department of Physiology and Pharmacology (1)

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Genome-Wide Expression Profiling of human tumor-infiltrating microglia/macrophages

Microglia isolated from glioma patients gain anti-tumor activities upon poly (I:C) stimulation. Expression profiles of human tumor-infiltrating microglia/macrophages before (untreated) and after treatment with poly (I:C) for 48h (induced). Tumor-infiltrating microglia/macrophages were isolated from ...

ORGANISM(S): Homo sapiens

2011-12-31 | E-GEOD-25289 | biostudies-arrayexpress

RNA sequencing of monocytes and microglia from mice with experimental autoimmune encephalomyelitis illustrates a changing phenotype with disease course

The role of microglia and infiltrating monocytes in experimental autoimmune encephalomyelitis (EAE) pathogenesis has been controversial. To gain insight into their respective roles, we developed a method for differentiating between microglia and infiltrating monocytes in the CNS using CD44. We used ...

ORGANISM(S): Mus musculus

2014-10-20 | E-GEOD-59725 | biostudies-arrayexpress

Transcription profiling of activated mixed glial (microglia) and monocyte-derived macrophages

Since macrophage activation can now be studied at a global level using modern microarray and proteomic analyses, discovery of novel macrophage activation genes is inevitable and important for understanding HIV-associated dementia (HAD). We isolated two different types of primary human macrophages, m...

ORGANISM(S): Homo sapiens

2007-08-29 | E-GEOD-1910 | biostudies-arrayexpress

Targeted Deletion of EMMPRIN in Microglia/Macrophages Mitigates Neuronal Death in Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) is a devastating subtype of stroke with high mortality and limited therapeutic options. Microglia and macrophages are myeloid cells that are rapidly recruited into ICH lesions where they contribute to secondary brain injury. However, the driver of myeloid cell neurotox...

ORGANISM(S): Mus musculus (Mouse)

2026-01-26 | PXD063205 | Pride

Interleukin-1 signaling is involved in local self-renewal and maintenance of microglia

During early embryogenesis microglia arise from yolk sac progenitors populating the developing CNS, where they are maintained as tissue-resident macrophages throughout the organism’s lifespan. Here, we describe an experimental system that allows the specific conditional ablation of microglia in vivo...

ORGANISM(S): Mus musculus

2015-07-15 | E-GEOD-68376 | biostudies-arrayexpress

Spinal cord injury (RNA sequencing data)

We investigated the gene expression profile of monocyte-derived macrophages and microglia following spinal cord injury. Moreover, we investigated the gene expression profole of M-CSF induced macrophages and new-born derived microglia following TGFb1 treatment. monocyte-derived macrophages and microg...

ORGANISM(S): Mus musculus

2014-12-03 | E-GEOD-62698 | biostudies-arrayexpress

Transcriptional profiling in microglia and peripheral macrophages phenotypes during development and neuroinflammation in mouse

Understanding the respective role of microglia and infiltrating monocytes in neuroinflammatory conditions has recently seemed possible by the identification of a specific microglia signature. Here instead we provide evidence that peripheral macrophages may express some of the most commonly described...

ORGANISM(S): Mus musculus

2020-10-12 | E-MTAB-8059 | biostudies-arrayexpress

Transcriptomes of Tgfbr2 Knockout Microglia and Macrophages

PRJNA436850 | ENA

F11R is a novel monocyte prognostic biomarker for malignant glioma [Affymetrix]

Objective: Brain tumors (gliomas) contain large populations of infiltrating macrophages and recruited microglia, which in experimental murine glioma models promote tumor formation and progression. Among the barriers to understanding the contributions of these stromal elements to high-grade glioma (g...

ORGANISM(S): Mus musculus

2013-11-13 | E-GEOD-46686 | biostudies-arrayexpress

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

Macrophages reside in essentially all tissues of the body and play key roles in innate and adaptive immune responses. Distinct populations of tissue macrophages also acquire context-specific functions that are important for normal tissue homeostasis. To investigate mechanisms responsible for tissue-...

ORGANISM(S): Mus musculus

2014-12-04 | E-GEOD-62826 | biostudies-arrayexpress

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