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MetabolomicsLipidome Alterations Following Mild Traumatic Brain Injury.
Not available
ORGANISM(S): Rattus norvegicus 
ST001950 | MetabolomicsWorkbench
TranscriptomicsChanges in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury
Warfare has long been associated with traumatic brain injury (TBI) in militarized zones. Common forms of TBI can be caused by a physical insult to the head-brain or by the effects of a high velocity blast shock wave generated by the detonation of an explosive device. While both forms of trauma are d...
ORGANISM(S): Mus musculus 
2013-03-18 | E-GEOD-44625 | biostudies-arrayexpress
GenomicsPlasma transcriptome profile in patients with mild traumatic brain injury
Plasma transcriptome profile in patients with mild traumatic brain injury
PRJNA419819 | ENA
TranscriptomicsRNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury
We assessed the roles of repopulating microglia in brain repair using mouse models. In this project, we show that removal of microglia from the mouse brain has little impact on the outcome of TBI but inducing the turnover of these cells through either pharmacologic or genetic approaches can yield a ...
ORGANISM(S): Mus musculus 
2020-02-15 | E-MTAB-8765 | biostudies-arrayexpress
ProteomicsProteomics characterization of the neuroprotective effects of low-dose methamphetamine on rats with traumatic brain injury (TBI)
Traumatic brain injury (TBI) causes hospitalizations and mortality worldwide with no approved neuroprotective treatments available, partly due to a poor understanding of the molecular mechanisms underlying TBI neuropathology and neuroprotection. We previously reported that the administration of low-...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-03-02 | PXD024317 | Pride
Ionstar Large-scale proteomics Traumatic brain injury Methamphetamine 
ProteomicsMultiomic analysis identifies involvement of complement-dependent pathways in outcomes after repetitive mild closed head injury
Repetitive mild closed head injury (rmCHI) is a common type of traumatic brain injury and its incidence is increasing, not least due to an increase in the number of sports-related injuries. The underlying neuroimmune mechanisms secondary to trauma that link rmCHI to cognitive decline are not well...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-01 | PXD053772 | Pride
Complement system Repetitive Rnaseq Cytof Traumatic brain injury Closed head Proteomics Microglia 
GenomicsWidespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury
Widespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury
PRJNA1190992 | ENA
TranscriptomicsPotential blood biomarkers for chronic traumatic encephalopathy: the multi-omics landscape of an observational cohort (serum exosomes miRNA microarray data)
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts, which is susceptible in elderly people with declined mobility, athletes of full contact sports, military personnel and victims of domestic violence. It has been pathologically d...
ORGANISM(S): Homo sapiens 
2022-10-18 | E-MTAB-12329 | biostudies-arrayexpress
TranscriptomicsPotential blood biomarkers for chronic traumatic encephalopathy: the multi-omics landscape of an observational cohort (serum-free RNA microarray data)
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts, which is susceptible in elderly people with declined mobility, athletes of full contact sports, military personnel and victims of domestic violence. It has been pathologically d...
ORGANISM(S): Homo sapiens 
2022-10-18 | E-MTAB-12330 | biostudies-arrayexpress
TranscriptomicsPotential blood biomarkers for chronic traumatic encephalopathy: the multi-omics landscape of an observational cohort (serum exosomes RNA microarray data)
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts, which is susceptible in elderly people with declined mobility, athletes of full contact sports, military personnel and victims of domestic violence. It has been pathologically d...
ORGANISM(S): Homo sapiens 
2022-10-18 | E-MTAB-12331 | biostudies-arrayexpress
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