mouse lung tissue

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Unknown (3033)
Transcriptomics (2895)
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Proteomics (270)
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Organisms

Mus musculus (2385)
Homo sapiens (513)
Arabidopsis thaliana (176)
Rattus norvegicus (56)
Drosophila melanogaster (19)
Sus scrofa (10)
Escherichia coli str. K-12 substr. MG1655 (9)
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Listeria monocytogenes EGD-e (2)
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Mus musculus domesticus (2)
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mixed sample (2)
Hordeum vulgare (2)
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Rhabdomys pumilio (1)
Cardamine sp. SIM-2007 (1)
Arabidopsis thaliana x Arabidopsis halleri (1)

Organisms

Mus musculus (813)
Homo sapiens (90)
Rattus norvegicus (4)
Mustela putorius furo (2)
Sus scrofa (2)
Francisella tularensis subsp. tularensis (1)
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Amia calva (1)
Mesocricetus auratus (1)
Mus (1)
Rattus (1)
gut metagenome (1)
mouse gut metagenome (1)
mouse metagenome (1)

Repository

biostudies-arrayexpress (2588)
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geo (595)
pride (177)
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Tissue

Lung (132)
Liver (48)
Heart (39)
Kidney (35)
Brain (32)
Spleen (30)
Testis (10)
Pancreas (8)
Skeletal muscle (8)
Colon (7)
Brown adipose tissue (5)
Thymus (3)
Stomach (3)
Ovary (3)
Adrenal gland (3)
Eye (2)
White adipose tissue (2)
Uterus (2)
Diaphragm (1)
Saliva-secreting gland (1)
Embryonic tissue (1)
Olfactory bulb (1)
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Midbrain (1)
Cerebral cortex (1)
Cortex of kidney (1)
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Renal medulla (1)

Disease

Normal (13)
Breast cancer (6)
Mammary tumor (3)
Porphyria NOS (2)
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Asthma (2)
Congential heart disease (1)
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LPS-induced acute lung injury (1)
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Unspecified peripheral T-cell lymphoma (1)
Perilobar nephrogenic rest (1)
CUP (1)
Lung adenocarcinoma (1)
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Xenografts with H1299 cell line (1)
Hodgkin lymphoma, mixed cellularity, stage IV (1)
MFC II (1)
Dukes D primary colon cancer (1)
Colon cancer metastasis (1)
IRAK-4 Q293X mutation (1)
Fibrosis (1)
Gestational diabetes mellitus (1)
None- acute control (1)
Hyperglycaemic (1)
Tuberculosis (1)
Small cell lung carcinoma (1)
SS2-infected (1)

Technology Type

Mass Spectrometry (181)
Shotgun proteomics (99)
Bottom-up proteomics (38)
Data-dependent acquisition (25)
Data-independent acquisition (21)
Mass spectrometry (20)
Mass spectrometry assay (14)
SWATH MS (13)
Top-down proteomics (8)
Affinity purification coupled with mass spectrometry proteomics (6)
ESI (4)
NMR spectroscopy (3)
Gel-based experiment (3)
NMR (2)
Proteogenomics (2)
SRM/MRM (2)
HiSeq X Ten (ILLUMINA) (1)
NMR spectroscopy assay (1)
DiaPASEF (1)

Instrument Platform

Illumina NovaSeq 6000 (110)
NextSeq 500 (73)
Illumina HiSeq 4000 (63)
Illumina HiSeq 2500 (57)
Illumina HiSeq 2000 (30)
NextSeq 550 (17)
Illumina MiSeq (14)
NextSeq 2000 (10)
Illumina NovaSeq X (9)
Axon GenePix 4000B scanning hardware (8)
Illumina HiSeq 3000 (6)
Illumina Genome Analyzer II (5)
DNBSEQ-T7 (5)
BGISEQ-500 (5)
Illumina HiSeq 1500 (5)
NA (4)
DNBSEQ-G400 (4)
Affymetrix GeneChip(R) HT Scanner (3)
Affymetrix GeneChip Scanner 3000 7G (3)
G2565BA DNA microarray scanner [Agilent] (3)
Scanning hardware (3)
Ion Torrent Proton (3)
Single-Cell Extraction: For enzymatic digestion, pronase (Septomyces argeus, 1 mg/mL) was applied for 25 minutes at room temperature for P0 to P8 datasets. Cells were dissociated and triturated into a single-cell suspension in ACSF supplemented with 1% fetal calf serum (FCS) and DNase (1 µL/10 mL). Trituration was performed using three glass Pasteur pipettes of decreasing diameters. For P30 datasets, enzymatic digestion and cell dissociation were carried out using the Worthington Papain Dissociation System, following the manufacturer’s instructions. Single-Nuclei Extraction: For nuclei isolation, the Hibernate™-E Medium was removed, and 500 µL of chilled 0.1X NP40 Lysis Buffer was added. Tissue was homogenized using a Pellet Pestle (15 strokes) and incubated on ice for 5 minutes. The suspension was pipette-mixed 10 times using a wide-bore pipette tip and incubated for an additional 10 minutes on ice. Following lysis, 500 µL of chilled wash buffer was added, and the mixture was pipette-mixed 5 times using a regular-bore pipette tip. The suspension was filtered through a 30 µm cell strainer into a 50 mL tube to remove debris. The filtered suspension was transferred to a 1.5 mL tube and centrifuged at 950 × g for 10 minutes at 4°C. The supernatant was carefully removed, and the nuclei pellet was retained for downstream analysis. (2)
Thermomixer (2)
10x Chromium (2)
ScanArray 4000 [PerkinElmer] (2)
GenePix Professional 4200A [Axon Instruments] (2)
BAS-5000 [FUJIFILM] (2)
Illumina Genome Analyzer IIx (2)
Axon- GenePix4000B (2)

Publication Date

2013 (302)
2015 (283)
2014 (257)
2012 (249)
2010 (241)
2011 (206)
2016 (203)
2025 (186)
2026 (174)
2008 (168)
2023 (158)
2022 (144)
2009 (135)
2024 (131)
2021 (121)
2020 (115)
2007 (84)
2019 (78)
2005 (67)
2017 (64)
2018 (62)
2006 (52)
2004 (13)
2003 (1)

UNIPROT ID/AC

MBD3_MOUSE (8)
E9Q6E5_MOUSE (8)
NHP2_MOUSE (8)
RL18A_MOUSE (8)
UIF_MOUSE (8)
PAF1_MOUSE (8)
CATIN_MOUSE (8)
WDR33_MOUSE (8)
HMGA1_MOUSE (8)
Q9EQC8_MOUSE (8)
TRA2B_MOUSE (8)
PDIP3_MOUSE (8)
SMCA2_MOUSE (8)
ARI1A_MOUSE (8)
SRS10_MOUSE (8)
CTCF_MOUSE (8)
TPP1_MOUSE (8)
DHB4_MOUSE (8)
COX2_MOUSE (8)
RL12_MOUSE (8)
GLYR1_MOUSE (8)
TOP2B_MOUSE (8)
RBM10_MOUSE (8)
CDC5L_MOUSE (8)
PRP4_MOUSE (8)
NCOA5_MOUSE (8)
FIP1_MOUSE (8)
SNW1_MOUSE (8)
SPF45_MOUSE (8)
HM20A_MOUSE (8)

CHEBI ID

CHEBI:55404 (1)
CHEBI:3110 (1)
CHEBI:27647 (1)
CHEBI:34498 (1)
CHEBI:1670 (1)
CHEBI:15630 (1)
CHEBI:28031 (1)
CHEBI:28870 (1)
CHEBI:27471 (1)
CHEBI:1296 (1)
CHEBI:1294 (1)
CHEBI:16142 (1)
CHEBI:17425 (1)
CHEBI:16852 (1)
CHEBI:15772 (1)
CHEBI:16523 (1)
CHEBI:17173 (1)
CHEBI:28834 (1)
CHEBI:16176 (1)
CHEBI:15816 (1)
CHEBI:33094 (1)
CHEBI:15548 (1)
CHEBI:28800 (1)
CHEBI:35432 (1)
CHEBI:17122 (1)
CHEBI:28666 (1)
CHEBI:17168 (1)
CHEBI:12194 (1)
CHEBI:30633 (1)
CHEBI:16094 (1)

Metabolite Name

Creatine (11)
Creatinine (10)
Adenosine (9)
Cytidine (9)
ADP (8)
Cytosine (8)
Anserine (8)
Choline (8)
Histamine (8)
Uridine (8)
Histidine (7)
Uracil (7)
Carnosine (7)
Pyridoxine (7)
Cholesterol (7)
Acetylcholine (7)
Taurine (7)
Phosphorylcholine (7)
Phenylalanine (7)
Adenine (7)
Guanosine (7)
Diethanolamine (6)
ATP (6)
CDP (6)
Valine (6)
CMP (6)
NAD+ (6)
Thiamine (6)
Niacinamide (6)
Guanine (6)

First Public Date

2025 (168)
2014 (138)
2026 (133)
2024 (122)
2023 (119)
2022 (82)
2021 (70)
2020 (57)
2019 (47)
2017 (44)
2015 (43)
2018 (35)
2016 (16)
2013 (10)

Lab affiliation

Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland (5)
Boehringer Ingelheim Pharma GmbH & Co. KG Drug Discovery Sciences (3)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (3)
Department of Biomedicine Faculty of medicine and Dentistry University of Bergen Service box 7804 N-5020 Bergen Norway (2)
Institute of Molecular Medicine and Experimental Immunology, BMZ-II, Building 12, University Hospital Bonn (2)
Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Division of Infection Medicine, Lund, Sweden (2)
Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchatel, Switzerland (2)
State Key Laboratory of Microbial Metabolism (2)
College of Chemistry and Molecular Engineering, Peking University, Beijing, China. (2)
Boston University (2)
Division Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, Germany (2)
State Key Laboratory of Oncogenes and Related Genes, Institute for Pearsonalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China (1)
Lydia Becker Institute of Immunology and Inflammation | Branch Lead for Immune Tolerance Division of Infection, Immunity & Respiratory Medicine| School of Biological Sciences I Faculty of Biology, Medicine and Health| The University of Manchester (1)
Deparment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea1Deparment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea (1)
Lydia Becker Institute of Immunology and Inflammation, University of Manchester, M13 9PL, United Kingdom (1)
Molecular Cell Biology, Weizmann Institute of Science (1)
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) (1)
Aging Institute, University of Pittsburgh School of Medicine/UPMC (1)
Max Planck Institute for Heart and Lung Research (1)
Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany (1)
"Philip Morris R&D, Neuchatel, Switzerland" (1)
Head, T cell Lab La Trobe Institute for Molecular Science, La Trobe University 1 Kingsbury Drive, Bundoora, Vic 3086 Australia (1)
Systems Biology Lab, Department of Life Science, National Taiwan University, Taiwan (1)
Helmholtz Zentrum München, Institute of Lung Biology and Disease, Member of the German Center for Lung Research (DZL), Munich, Germany (1)
Department of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang, Henan, 471023, China (1)
Faculty of Medicine, University of Heidelberg, 69120 Heidelberg, Germany Division Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany (1)
Director, Institute for Tissue Engineering and Regenerative Medicine (iTERM) Helmholtz Zentrum München Ingolstädter Landstraße 1 85764 Neuherberg Germany (1)
Institute of Medical Microbiology, University of Zurich (1)
Washington University, Department of Medicine, Division of Pulmonary and Critical Care (1)
Fudan University, Huashan Hospital (1)

IsPrivate

False (1)

Model Flag

Non Kinetic (1)

Classification

bacteria (1)

Modification

6-dioxaoctanediamine derivatized cysteine (1)

Study type

Transcription profiling by array (1629)
RNA-seq of coding RNA (341)
ChIP-seq (152)
RNA-seq of coding RNA from single cells (95)
Other (35)
Animal - High-throughput sequencing (27)
Comparative genomic hybridization by array (25)
Unknown experiment type (24)
ChIP-chip by tiling array (24)
ChIP-chip by array (24)
Methylation profiling by array (24)
Methylation profiling by high throughput sequencing (22)
RNA-seq of non coding RNA (19)
Transcription profiling by RT-PCR (17)
DNA-seq (14)
RNA-seq of total RNA (12)
Cell line - High-throughput sequencing (11)
ATAC-seq (10)
Transcription profiling by tiling array (8)
Animal - One-color microarray (6)
MicroRNA profiling by array (6)
Transcription profiling by SAGE (4)
Genotyping by array (4)
Single nucleus RNA sequencing (4)
Differential (3)
Human - High-throughput sequencing (3)
CLIP-seq (3)
Spatial transcriptomics by high-throughput sequencing (3)
Hi-C (3)
CUT&RUN (3)

Release Date

2022 (382)
2023 (359)
2025 (357)
2014 (356)
2021 (356)
2013 (354)
2015 (347)
2024 (346)
2016 (318)
2020 (316)
2012 (295)
2010 (269)
2011 (254)
2019 (230)
2018 (195)
2017 (195)
2008 (186)
2009 (155)
2007 (97)
2026 (87)
2005 (76)
2006 (54)
2004 (14)
2003 (6)
1997 (5)
2002 (4)
2000 (4)
1999 (2)
1998 (2)

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Spatially resolved integrative analysis of transcriptomic and metabolomic changes in tissue injury studies

Recent developments in spatially resolved -omics have enabled the joint study of gene expression, metabolite levels and tissue morphology, offering greater insights into biological pathways. Integrating these modalities from matched tissue sections to probe spatially-coordinated processes, howeve...

2025-12-03 | MTBLS13445 | MetaboLights

Mouse Brown Adipose Tissue Lipidomics under Cold and Dietary Fat Interventions

This study investigates lipidomic remodeling in mouse brown adipose tissue under a 2 × 3 experimental design involving environmental condition and dietary fatty acid composition. Mice were maintained at room temperature with ad libitum feeding or exposed to 4°C cold conditions with 70% calorie restr...

2026-06-01 | MTBLS14642 | MetaboLights

Lactobacillus johnsonii-derived oxindole protects acute lung injury by reducing CXCL13

Gut microbiota is altered in mice with acute lung injury (ALI). Supplementation with Lactobacillus johnsonii, which is deficient in it, improved ALI in mice, and we elucidated the underlying mechanisms of the improvement by metabolomics.

2026-02-12 | MTBLS11438 | MetaboLights

Transcription profiling of mouse secondary alveolar septae of neonatal lung tissue

The tips of secondary alveolar septae in day 6 neonatal mouse lung tissue were isolated using laser capture microscopy. RNA was isolated from pooled secondary alveolar tips and also from pooled neonatal day 6 whole lung tissue. The isolated RNAs were then amplified in parallel. Gene array profiling ...

ORGANISM(S): Mus musculus

2008-06-12 | E-GEOD-4220 | biostudies-arrayexpress

Metabolic profiling of mouse tissues and tissue interstitial fluids

Not available

ORGANISM(S): Mus musculus

ST002223 | MetabolomicsWorkbench

Ten Mouse Organs Proteome and Metabolome Atlas from Adult to Aging

The complexity of the aging process, encompassing numerous organs and systems, poses a significant challenge in identifying and targeting key factors that drive age-related decline. The multi-organ synchronous molecular intricacies underlying natural aging remain elusive. Here we presented a data...

2025-08-29 | MTBLS10642 | MetaboLights

Quantitative metabolomics of plasma and tissue interstitial fluids from mice

This study presents quantitative metabolomic measurements of plasma and tissue interstitial fluids (IF) collected from healthy C57BL/6J mice. Using liquid chromatography–mass spectrometry (LC–MS) and external chemical standards, absolute concentrations were determined for over one hundred polar m...

2025-12-30 | MTBLS13165 | MetaboLights

Transcription profiling of mouse lung tissue after exposure to mainstream tobacco smoke

We have examined the impact of subchronic levels of tobacoo smoke on murine lungs. We have used high density DNA microarray and analysed lung tissues from mice exposed to mainstream tobacco smoke (MTS). Our results reveal induction of inflammatory cytokine interleukin-6 (IL-6) and its antagonist sup...

ORGANISM(S): Mus musculus

2009-09-18 | E-GEOD-12930 | biostudies-arrayexpress

Progressive genomic instability in the FVB/KrasLA2 mouse model of lung cancer

Alterations in DNA copy number contribute to the development and progression of cancers and are common in epithelial tumors. We have used array Comparative Genomic Hybridization (aCGH) to visualize DNA copy number alterations across the genomes of lung tumors in the KrasLA2 model of lung cancer. C...

ORGANISM(S): Mus musculus

2011-11-22 | E-GEOD-29230 | biostudies-arrayexpress

Fecal Microbiota Transplantation Restores Gut Homeostasis and Enhances ER-Phagy to Mitigate Radiation-Induced Lung Injury

Radiation-induced lung injury (RILI) is a severe side effect of radiation therapy, characterized by lung tissue damage, inflammation, and organ dysfunction. Although fecal microbiota transplantation (FMT) has shown potential in alleviating radiation-induced damage, its underlying mechanisms ...

2026-01-05 | MTBLS12699 | MetaboLights

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