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ProteomicsIntegrated Proteogenomic Characterization of Localized Prostate Cancer Identifies Biological Insights and Subtype-Specific Therapeutic Strategies
We profiled the genome, transcriptome, proteome and phosphoproteome of 145 cases of localized prostate cancer (PCa) in Chinese patients and revealed three subtypes with distinct molecular features. We integrated multi-omic data to refine molecular subtyping of localized PCa, and identified NANS as a...
ORGANISM(S): Homo Sapiens 
PXD056748 |
TranscriptomicsAn integrative multi-platform analysis for biomarker discovery of osteosarcoma
Three osteosarcoma (OS) cell lines (MG-63, Saos-2 and U-2 OS) and 1 osteoblastic cell line (hFOB1.19) were collected for this work. MG-63 was kindly provided by Dr. Agi Grigoriadis from University College London. Saos-2, U-2 OS and hFOB1.19 were purchased from ATCC. All cells used were kept in expon...
ORGANISM(S): Homo sapiens 
2011-09-15 | E-GEOD-14789 | biostudies-arrayexpress
UnknownTGx-DDI (toxicogenomic DNA damage-inducing) biomarker validation: multi-site ring trial supporting regulatory use.
Not available
S-EPMC12646585 | biostudies-literature
UnknownPrognostic value and early response stratification of a multi-biomarker panel in cervical cancer patients undergoing chemoradiotherapy.
Not available
S-EPMC12611648 | biostudies-literature
UnknownBlood Biomarker-Based Predictive Indicator for Liver Metastasis in Alpha-Fetoprotein-Producing Gastric Cancer and Multi-Omics Tumor Microenvironment Insights.
Not available
S-EPMC12302549 | biostudies-literature
UnknownIdentification of CWH43 as a novel prognostic biomarker and therapeutic target in clear cell renal cell carcinoma by a multi-omics approach and correlation with autophagy progression.
Not available
S-EPMC12167738 | biostudies-literature
UnknownIntegrated multi-omics analysis identifies TPX2 as a potential prognostic and immunological biomarker in hepatocellular carcinoma.
Not available
S-EPMC12496236 | biostudies-literature
Methylation profilingIntegrated biomarker and treatment correlates of prognosis in infant medulloblastoma: Multi-national retrospective cohort studies
This dataset spans two studies which investigate the clinico-pathology and molecular features of infant medulloblastoma, defined as children aged <5 years at diagnosis. Both abstracts follow. Background Infant medulloblastoma (iMB; <3-5-years old at diagnosis) is a major challenge in paediatric onco...
ORGANISM(S): Homo sapiens 
2026-05-29 | GSE317378 | GEO
ProteomicsClinical proteomics reveals vulnerabilities in non-invasive breast ductal carcinoma and drives personalized treatment strategies
Ductal carcinoma in situ (DCIS) is the most common type (80%) of non-invasive breast lesions in women. The lack of validated prognostic markers, limited patient numbers, and variable tissue quality have a significant impact on diagnosis, risk stratification, patient enrolment, and the results of cli...
ORGANISM(S): Homo sapiens (Human) 
2024-12-31 | PXD040782 | Pride
Multi-omics Clinical proteomics Cancer research Biomarker 
ProteomicsAffinity capture enrichment versus Affinity depletion: A comparison of strategies for increasing coverage of low abundant human plasma proteins
present study, we evaluated four small molecule affinity-based probes based on agarose-immobilized benzamidine (ABA), O-Phospho-L-Tyrosine (pTYR), 8-Amino-hexyl-cAMP (cAMP), or 8-Amino-hexyl-ATP (ATP) for their ability to remove high-abundant proteins such as serum albumin from plasma samples thereb...
ORGANISM(S): Homo sapiens (Human) 
2020-08-27 | PXD020727 | Pride
Affinity enrichment Depletion Human plasma 
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