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TranscriptomicsIdentification of a microRNA regulator for axon guidance in the olfactory bulb of adult mice
Using the highly sensitive miRNA array, we screened 40 microRNAs abundant in the olfactory bulb and we explored the functions of these miRNAs in the olfactory bulb by Gene Ontology and Kyoto Encyclopedia of Genes annotation. The enrichment results indicated that these miRNAs mainly participated in t...
ORGANISM(S): Mus musculus 
2014-08-27 | E-GEOD-55463 | biostudies-arrayexpress
MetabolomicsCholic Acid as a Potential Mediator in PD Olfactory Dysfunction: Insights from Nasal Microbiome-Metabolite Interactions Research

Background: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by both motor and non-motor symptoms, including olfactory dysfunction, which often precedes motor symptoms by several years. However, the underlying mechanisms linking olfactory dysfunction in PD to bio...

2025-07-07 | MTBLS12692 | MetaboLights
ProteomicsA proteomic analysis of human olfactory bulb
Olfactory sensory neurons distinguish a large variety of odor molecules and direct the information through their axons to the olfactory bulb, the first site for the processing of olfactory information in the brain. Olfaction is very important for most mammals for the maintenance of a good quality of...
ORGANISM(S): Homo sapiens (Human) 
2017-08-23 | PXD005629 | Pride
Tissue Brplc Ltq-orbitrap Protein biomarkers Neuroproteomics. 
TranscriptomicsEffect of rabies virus infection on gene expression in GABAergic neurons in the Zebrafish olfactory bulb
To investigate the effects of rabies infection on neuronal gene expression, we compared gene profiles of rabies infected and non-infected GABAergic neurons in the Zebrafish olfactory bulb.
ORGANISM(S): Danio rerio 
2022-07-07 | E-MTAB-11083 | biostudies-arrayexpress
ProteomicsAcetylome Analyses Provide New Insights into the Effects of Childhood Allergic Rhinitis on Olfactory Bulb-Dependent Olfactory Impairment
Background: Allergic rhinitis (AR) is a global health burden affecting 20% of the pediatric population and is characterized by nasal inflammation and frequent olfactory dysfunction. Protein acetylation, which is a frequently occurring posttranslational modification, plays pivotal roles in the regula...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD066708 | Pride
Allergic rhinitis  children  olfactory dysfunction  olfactory bulb  lysine acetylation 
TranscriptomicsGenome-wide expression analysis of E18.5 and P30 olfactory bulbs of control and Tshz1 mutant mice
Analysis of genes regulated by Tshz1 in olfactory bulb neurons. Total RNA from olfactory bulbs of embryonic day E18.5 and postnatal day 30 control mice was compared to Tshz1 mutant mice
ORGANISM(S): Mus musculus 
2023-10-12 | E-GEOD-51761 | biostudies-arrayexpress
ProteomicsOlfactory bulb proteomics in human Alzheimer's disease
Olfactory dysfunction is among the earliest features of Alzheimer´s disease (AD). Although neuropathological abnormalities have been detected in the olfactory bulb (OB), little is known about its dynamic biology. Here, OB- proteome analysis was performed across different AD stages using a label-free...
ORGANISM(S): Homo sapiens (Human) 
2018-01-16 | PXD005319 | Pride
Proteomics Olfactory bulb 
TranscriptomicsTranscription profiling of mouse olfactory epithelium frpm Harlequin mutants compared to littermate controls
Microarray analysis of gene expression in the olfactory epithelium of Harlequin mouse as a model of oxidative-stress induced neurodegeneration of olfactory sensory neurons Experiment Overall Design: Olfactory epithelium from Harlequin mutant mice and littermate control mice was microdissected for RN...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6485 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the olfactory bulb of mice induced by exposure to diesel exhaust are dependent on animal rearing environment
There is an emerging concern that particulate air pollution increases the risk of cranial nerve disease onset. Small nanoparticles, mainly derived from diesel exhaust particles reach the olfactory bulb by their nasal depositions. It has been reported that diesel exhaust inhalation causes inflammatio...
ORGANISM(S): Mus musculus 
2013-04-18 | E-GEOD-46163 | biostudies-arrayexpress
ProteomicsOlfactory bulb proteome characterization in APP/PS1 mice
Here we used double-transgenic amyloid precursor protein/presenilin 1 (APPswe/PS1dE9) mice and label-free quantitative proteomics to analyze potential early pathological effects on the olfactory bulb (OB) during AD progression.
ORGANISM(S): Mus musculus (Mouse) 
2016-08-09 | PXD003683 | Pride
Olfactory bulb Proteomics 
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