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TranscriptomicsRegulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
The apolipoprotein A-I (apoA-I) mimetic peptide 4F displays prominent anti-inflammatory properties, including the ability to reduce vascular macrophage content. Macrophages are a heterogenous group of cells, represented by two principal phenotypes, the classically activated M1 macrophage and an alt...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-36933 | biostudies-arrayexpress
ProteomicsPeptidoglycan metabolite photoaffinity reporters reveal direct binding to intracellular pattern recognition receptors and Arf GTPases
Extensive structure-activity studies of iE-DAP and MDP have demonstrated their selective activation of NOD1- and NOD2-expressing cells, respectively. Nonetheless, the direct binding of iE-DAP and MDP to NOD1 and NOD2, respectively, as well as other proteins in mammalian cells has not been systematic...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012350 | Pride
Mdp Gel-based proteomics Nod2 Hek293t 
TranscriptomicsGene expression study reveals compromised Pattern Recognition Receptors and Interferon Signaling in fullterm Low birth Weight newborns
Low Birth Weight (LBW) newborns (with weight less than 2500g) suffer a higher frequency and severity of microbial infection than normal birth weight (NBW) newborns. Morbidity and mortality of LBW infants due to infectious diseases are known to be high and it has been associated with compromised immu...
ORGANISM(S): Homo sapiens 
2012-01-15 | E-GEOD-29807 | biostudies-arrayexpress
ProteomicsGenotyping-by-sequencing-based identification of Arabidopsis pattern recognition receptor RLP32 recognizing proteobacterial translation initiation factor IF1
Pattern-triggered immunity (PTI) is a central component of plant immunity. Activation of PTI relies on the recognition of microbe-derived structures, termed patterns, through plant encoded surface-resident pattern recognition receptors (PRRs). We have identified proteobacterial translation initiatio...
ORGANISM(S): Escherichia coli 
2022-03-03 | PXD031124 | Pride
Pattern recognition receptor Proteobacterial protein translation initiation factor 1 Plant immunity 
ProteomicsDiverse bacterial pattern recognition receptors sense the core phage proteome
Recognition of foreign molecules inside cells is critical for immunity across all domains of life. Proteins of the STAND NTPase superfamily, including eukaryotic NOD-like receptors (NLRs), play a central role in this process. In bacteria and archaea, although several STAND families sense phage prote...
ORGANISM(S): Salmonella enterica Escherichia coli Escherichia phage T1 
2026-06-10 | PXD079457 | Pride
Seavs7  stand ntpase  bacterial immunity  antiphage defense  phage major capsid protein  ef-tu  affinity purification mass spectrometry  pulldown proteomics  tmtpro 
UnknownPattern recognition receptors in health and diseases.
Not available
S-EPMC8333067 | biostudies-literature
GenomicsCancer immunotherapy targeting murine myeloid cells requires endosomal pattern recognition
Cancer immunotherapy targeting murine myeloid cells requires endosomal pattern recognition
PRJNA1298211 | ENA
GenomicsBacterial pattern recognition in C. elegans by the nuclear hormone receptor NHR-86/HNF4
Bacterial pattern recognition in C. elegans by the nuclear hormone receptor NHR-86/HNF4
PRJNA835140 | ENA
UnknownSmall molecule modulators of immune pattern recognition receptors.
Not available
S-EPMC10685800 | biostudies-literature
UnknownPattern-recognition receptors and gastric cancer.
Not available
S-EPMC4105827 | biostudies-literature
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