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MetabolomicsFunctional targeting of PTTG1 in pericytes restores vascular integrity in diabetic retina
Pericyte loss is an early and critical event in the pathogenesis of diabetic retinopathy (DR), yet the molecular mechanisms underlying pericyte dysfunction remain incompletely understood. Using single-cell RNA sequencing, we generated a retinal cellular overview comprising 37,982 cells from diabetic...
2026-03-30 | MTBLS14184 | MetaboLights
MetabolomicsFunctional targeting of PTTG1 in pericytes restores vascular integrity in diabetic retina

Pericyte loss is an early and critical event in the pathogenesis of diabetic retinopathy (DR), yet the molecular mechanisms underlying pericyte dysfunction remain incompletely understood. Using single-cell RNA sequencing, we generated a retinal cellular overview comprising 18,926 cells from...

2026-03-27 | MTBLS13544 | MetaboLights
ProteomicsProteomic data for tumor pericytes derived from colorectal cancer patients
This study aims to investigate differentially expressed proteins in tumor pericytes derived from colorectal cancer patients with or without liver metastasis. Tumor pericytes were isolated from tumor of colorectal cancer patients with or without liver metastasis. Then, tumor pericytes were cultured a...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD033011 | Pride
Metastasis colorectal cancer Tumor pericytes 
TranscriptomicsRNA-seq of mouse pancreatic pericytes from wild-type and Tcf7l2-mutated mice
To characterise their gene expression, wild type pancreatic pericytes were isolated based on the YFP-labeling from Nkx3.2-Cre;EYFP mice. As control, whole isolated islets were analysed.To identify Tcf7l2-depenedent genes, pancreatic pericytes were isolated from Nkx3.2-Cre;EYFP;Tcf7l2 flox/flox trans...
ORGANISM(S): Mus musculus 
2017-12-14 | E-MTAB-5325 | biostudies-arrayexpress
ProteomicsProteomic data for tumor pericytes with TCFA2 overexpression
This study aims to investigate differentially expressed proteins in tumor pericytes with or without TCAF2-ovexpression. Tumor pericytes were isolated from tumor of patients with colorectal cancer. Then, tumor pericytes were cultured, transfected with vector or TCAF2 overexpressing plasmid. Top ten c...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD032935 | Pride
Tcaf2 Tumor pericytes 
TranscriptomicsTranscription profiling of human dermal pericytes compared to the remaining dermal cells of neonatal human foreskin
Pericytes derived from skin dermis can substantially enhance the short-term tissue-regenerative capacity of human epidermal cells already committed to differentiation; they also display both phenotypic and functional properties of mesenchymal stem cells. In this microarray analysis, we compared the ...
ORGANISM(S): Homo sapiens 
2009-10-10 | E-GEOD-17014 | biostudies-arrayexpress
ProteomicsContraction of brain pericytes in response to Islet Amyloid PolyPeptide is reversed by pramlintide.
The islet amyloid polypeptide (IAPP), a pancreas-produced peptide, has beneficial functions in its monomeric form. However, IAPP aggregates, related to type 2 diabetes mellitus (T2DM), are toxic not only for the pancreas, but also for the brain. In the latter, IAPP is often found in vessels, where i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035048 | Pride
Amylin Vasculopathy Blood-brain barrier Diabetes Lc-ms/ms 
TranscriptomicsAge-dependent RGS5 loss in pericytes induces cardiac dysfunction and fibrosis in the heart (Bulk RNA-SEQ)
Background. Ageing is one of the main risk factors of cardiovascular disease. Pericytes are capillary-associated mural cells involved in the maintenance and stability of the vascular network. In the heart, the consequences of ageing on cardiac pericytes are unknown. Methods. In this study, we have ...
ORGANISM(S): Homo sapiens 
2024-03-13 | E-MTAB-13833 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profile of human placental pericytes
The objective of this array was to determine the global gene expression profile of human placental pericytes for comparison with other publicly available arrays of pericytes and mesenchymal stromal cells isolated from various human tissues. Pericytes are critical cellular components of the microvas...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-21332 | biostudies-arrayexpress
GenomicsDissecting CD248 role in tumor pericytes
Dissecting CD248 role in tumor pericytes
PRJNA578930 | ENA
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