Sort   by:  
 Page size 
MetabolomicsAMPK activation orchestrated replicative senescence of periodontal ligament stem cells via regulating metabolomics

BACKGROUND: Periodontal ligament mesenchymal stem cells (PDLSCs) are a promising cell resource for cell-based regenerative medicine in dentistry. PDLSCs inevitably acquire a senescent phenotype after prolonged in vitro expansion, and the key regulators of cells during replicative...

2022-11-15 | MTBLS4568 | MetaboLights
TranscriptomicsComparative gene expression analysis of dental follicle and periodontal ligament in humans
The aim of this study was to evaluate and compare the gene expression profiles of dental follicle and periodontal ligament in humans, which can possibly explain their functions of dental follicle and PDL such as eruption coordination and stress resorption. That may apply this information to clinical...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-51342 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chronic inflamed and healthy periodontal ligament cells in vivo
The periodontium are the tissues supporting and investing the tooth and consists of the periodontal ligament, the gingiva, the root cementum, and the alveolar bone. The functions of the cell populations in health and disease regarding the host-mediated tissue destruction are not well understood. To ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7321 | biostudies-arrayexpress
TranscriptomicsComparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth
There are histological and functional differences between human deciduous and permanent pediodontal ligament (PDL) tissues. The purpose of this study was to determine the differences between these two types of tissue at the molecular level by comparative gene expression analysis. PDL samples were ob...
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-50640 | biostudies-arrayexpress
ProteomicsProteomic profile of rat periodontal tissues in health and periodontal disease
The periodontal ligament tissue plays a crucial role in oral functions by providing structural support to the tooth. Due to the presence of undifferentiated mesenchymal cells, research into its regenerative capacity is ongoing. Pathological conditions can affect these functions and protein compositi...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-01 | PXD055817 | Pride
Lc-msms C5 Periodontal ligament Lgals3 Proteomics Serpinb1 Periodontitis 
TranscriptomicsExpression of M-CSF from cryopreserved teeth-derived human periodontal ligament cells with different freezing protocols
This study investigated which genes regarding root resorption are upregulated by cryopreservation and whether cryopreservation affects the expression of Macrophage M-bM-^@M-^Scolony stimulating factor. We manufactured the customized template which was made of genes selected regarding root resorption...
ORGANISM(S): Homo sapiens 
2013-01-19 | E-GEOD-43611 | biostudies-arrayexpress
ProteomicsLFQ and SRM proteome analysis of Saliva reveals transition signatures from health to periodontal disease
Phase 1: The whole saliva samples were obtained from 66 systemically healthy subjects consisting of patients with chronic periodontitis (CP), generalized aggressive periodontitis (G-AgP), gingivitis and individuals with periodontal health. The use of humans for study satisfied the requirements of th...
ORGANISM(S): Homo sapiens (Human) 
2018-04-10 | PXD007535 | Pride
Data integration Lfq Srm Lc-ms/ms 
TranscriptomicsFunction of chemokine (CXC motif) ligand 12 in periodontal ligament fibroblasts
The periodontal ligament (PDL) is one of the connective tissues located between the tooth and bone. It is characterized by rapid turnover. Periodontal ligament fibroblasts (PDLFs) play major roles in the rapid turnover of the PDL. Microarray analysis of human PDLFs (HPDLFs) and human dermal fibrobla...
ORGANISM(S): Homo sapiens 
2013-11-07 | E-GEOD-52162 | biostudies-arrayexpress
GenomicsDifferential DNA methylation in gingival tissues in periodontal health and disease [Array]
Differential DNA methylation in gingival tissues in periodontal health and disease [Array]
PRJNA723763 | ENA
ProteomicsSARS-CoV-2 infection causes periodontal fibrotic pathogenesis through deregulating mitochondrial beta-oxidation
The global high prevalence of COVID-19 is a major challenge for health professionals and patients. SARS-CoV-2 virus has four kinds of structural protein components: the spike protein, envelope protein, membrane protein, and nucleocapsid protein. SARS-CoV-2 virus mutate predominantly in the spike pro...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD041281 | Pride
Covid19 Periodontal Infection 
Sort   by:  
 Page size