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TranscriptomicsTranscription profiling of mouse spinal cord and dorsal root ganglion to test the fundamental quantitative differences between central and peripheral nervous system transcriptomes
We used microarrays to test the fundamental quantitative differences between central and peripheral nervous system transcriptomes. Experiment Overall Design: 3 independent SC and 3 independent DRG samples were analyzed. Each sample contained material from 4 age-matched male C57B/6 mice.
ORGANISM(S): Mus musculus 
2007-11-27 | E-GEOD-5425 | biostudies-arrayexpress
MetabolomicsMetabolome profiling by untargeted metabolomics and biomarker panel selection using machine-learning for patients in different stages of peripheral neuropathy induced by oxaliplatin

Background: Oxaliplatin-induced peripheral neuropathy (OIPN) poses a significant challenge for patients with colorectal tumor, often resulting in treatment interruption or discontinuation and subsequent treatment failure. Herein, a longitudinal untargeted metabolomic study to reveal the metabolom...

2025-08-14 | MTBLS12854 | MetaboLights
Transcriptomicshuman peripheral nervous system SAGE
expression profiles generated from sciatic nerve as well as from Schwann cells cultured thereof Keywords: other
ORGANISM(S): Homo sapiens 
2005-04-16 | E-GEOD-2529 | biostudies-arrayexpress
TranscriptomicsLineage-dependent spatial and functional organisation of the mammalian enteric nervous system
Single-cell transcriptomic analysis to delineate key regulators of neurogenic commitment in the enteric nervous system. To resolve the molecular profiles of ENCCs and identify transcriptional signatures of lineage restriction and differentiation, we analyzed their transcriptomes by single-cell RNA-s...
ORGANISM(S): Mus musculus 
2020-07-27 | E-MTAB-5553 | biostudies-arrayexpress
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS380 | MetaboLights
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS382 | MetaboLights
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
TranscriptomicsGenomic aberrations in primary central nervous system lymphoma (PCNSL)
Genomic aberrations in primary central nervous system lymphoma (PCNSL). Two-condition experiment, PCNSLs vs. healthy men. Biological replicates: 12 tumors replicates, 13 peripheral blood replicates.
ORGANISM(S): Homo sapiens 
2010-11-13 | E-GEOD-25298 | biostudies-arrayexpress
TranscriptomicsEssential roles for the splicing regulator nSR100/SRRM4 during nervous system development
Alternative splicing (AS) generates vast transcriptomic complexity in the vertebrate nervous system. However, the extent to which trans-acting splicing regulators and their target AS regulatory networks contribute to nervous system development is not completely understood. To address these questions...
ORGANISM(S): Mus musculus 
2015-04-14 | E-GEOD-65818 | biostudies-arrayexpress
ProteomicsDistribution of big tau isoforms in the human central and peripheral nervous system
‘Big tau’, a longer isoform of tau is expressed in peripheral nervous system (PNS) and specific regions of the central nervous system (CNS). Big tau distribution across the human nervous system and pathophysiological role remains largely unknown. Here, using mass spectrometry, we demonstrate the big...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD059267 | Pride
Tau protein Nerve Proteomics Brain Alzheimer's disease Spinal cord Lc-ms/ms 
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