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TranscriptomicsExpression data from mouse optic nerve head after optic nerve crush
Reactive gliosis is a complex process that involves profound changes in gene expression. We used microarray to indentify differentially expressed genes and to investigate the molecular mechanisms of reactive gliosis in optic nerve head in response to optic nerve crush injury. C57Bl/6 female mice wer...
ORGANISM(S): Mus musculus 
2013-07-15 | E-GEOD-40857 | biostudies-arrayexpress
MetabolomicsLipidomics of inflammation-induced optic nerve regeneration
Not available
ORGANISM(S): Rattus norvegicus 
ST000963 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling time series of rat retina after intra-orbital nerve transection, intra-orbital nerve crush or no treatment
Array experiment: Animals were divided into a control group (naive), which did not undergo any experimental manipulation (n=20) and two experimental groups, one receiving an intra-orbital nerve transection (IONT, n=60) and the other an intra-orbital nerve crush (IONC, n=60) Sterile precautions were ...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-MEXP-1387 | biostudies-arrayexpress
ProteomicsQuantitative Mass Spectrometry Analysis of the Injured Proximal and Distal Human Digital Nerve Ends
Proteomic analysis of injured human peripheral nerves, particularly focusing on events occurring in the proximal and distal nerve ends, remains relatively underexplored. This study aimed to investigate the molecular patterns underlying a digital nerve injury, concentrating on differences in protein ...
ORGANISM(S): Homo sapiens (Human) 
2024-07-19 | PXD051266 | Pride
Digital nerve injury Quantitative mass spectrometry Signal transduction Peripheral nerve injury Nerve injury pathways Extracellular matrix Proteomics 
TranscriptomicsDifferential response of C57BL/6J mouse and DBA/2J mouse to optic nerve crush
Retinal ganglion cell (RGC) death is the final consequence of many blinding diseases, where there is considerable variation in the time course and severity of RGC loss. Indeed, this process appears to be influenced by a wide variety of genetic and environmental factors. In this study we explored the...
ORGANISM(S): Mus musculus 
2010-08-19 | E-GEOD-17117 | biostudies-arrayexpress
ProteomicsThe proteome of human retrobulbar optic nerve
The optic nerve is a white matter tract that conveys visual information to the brain. A detailed investigation of the proteome of the normal human retrobulbar optic nerve may help facilitate studies of the biology and pathophysiology of the optic nerve. We conducted an in-depth proteomic analysis of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-13 | MSV000081934 | MassIVE
TranscriptomicsMicroarray Analysis Gene Expression Profiles in Laryngeal Muscle After Recurrent Laryngeal Nerve Injury
The pathophysiology of recurrent laryngeal nerve (RLN) transection injury is rare in that it is characteristically followed by a high degree of spontaneous reinnervation, with reinnervation of the laryngeal adductor complex (AC) preceding that of the abducting posterior cricoarytenoid (PCA) muscle. ...
ORGANISM(S): Rattus norvegicus 
2016-07-01 | E-GEOD-72361 | biostudies-arrayexpress
MetabolomicsAlleviation of Loperamide-Induced Constipation by Lactiplantibacillus plantarum SYS1: Role of Properistaltic Metabolites and Promotion of Enteric Nerve Development via 5-HT4R Activation

Background: Constipation is a common gastrointestinal disorder. Lactobacillus plantarum has been reported to have the effect of relieving constipation, but its underlying mechanism remains unclear.

Results: Lactiplantibacillus plantarum SYS1 was identified through in ...

2025-08-06 | MTBLS12821 | MetaboLights
MetabolomicsLipid profile Dataset of optogenetics induced optic nerve regeneration
Not available
ORGANISM(S): Mus musculus 
ST001381 | MetabolomicsWorkbench
MetabolomicsHuman Optic Nerve Glaucoma and Control Lipidomes
Not available
ORGANISM(S): Homo sapiens 
ST001442 | MetabolomicsWorkbench
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