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MetabolomicsEpithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic
Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A2 group 1B (PLA2g1B) as a host-derived endogenous anthelmintic. PLA2g1B is elevated in resistant mice an...
2018-08-13 | MTBLS523 | MetaboLights
MetabolomicsThe interaction of ceramide-1-phosphate with group IVA cytosolic phospholipase A2 modulates neutrophil polarization during inflammatory responses
Not available
ORGANISM(S): Mus musculus 
ST002445 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human HepG2 cells overexpressing GPI-phospholipase D vs control sampled at 2 time points
A time course of the effect of overexpressing GPI-PLD on global gene expression in HepG2 cells was compared to control virus. Experiment Overall Design: This experiment compares the global gene expression in HepG2 cells that were either transduced with an adenovirus expressing GPI-phospholipase D or...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4731 | biostudies-arrayexpress
UnknownExpression of enzymatically inactive wasp venom phospholipase A1 in Pichia pastoris.
Not available
S-EPMC3121754 | biostudies-literature
UnknownCrystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain.
Not available
S-EPMC9000616 | biostudies-literature
TranscriptomicsTranscription profiling of rat heart tissue from animals aged 4 and 22 months
Myocardial aging leads to a reduction of beta-adrenergic receptor-induced metabolic and contractile responsiveness. We hypothesize that a change in the patterns of gene expression is important in these age-related events. To test this, hearts were harvested from young and aged male rats (3-4 and 20-...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-421 | biostudies-arrayexpress
UnknownPhosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation.
Not available
S-EPMC4338883 | biostudies-literature
ProteomicsMurine and human bile proteome analysis
The gut microbiota is known to influence host metabolism, but its impact on lipid uptake from the nutrition and underlying mechanisms remain mysterious. Combining lipidomics and proteomics we discovered a microbiome-related phospholipase A1 (PLA1) activity in bile.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-07-30 | PXD033894 | Pride
Proteomics Pla activity Cel Phospholipase a1 Bile 
UnknownCharacterization of the Intrinsic Phospholipase A1 Activity of Bordetella pertussis Adenylate Cyclase Toxin.
Not available
S-EPMC6316389 | biostudies-literature
GenomicsPhosphatidylserine phospholipase A1 enables GPR34-dependent immune cell accumulation in the peritoneal cavity
Phosphatidylserine phospholipase A1 enables GPR34-dependent immune cell accumulation in the peritoneal cavity
PRJNA1147582 | ENA
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