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MetabolomicsProteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation

Saccharomyces cerevisiae is a widely used cell factory; therefore, it is important to understand how it organizes key functional parts when cultured under different conditions. Here, we perform a multiomics analysis of S. cerevisiae by culturing the strain with a wide range of s...

2022-08-31 | MTBLS697 | MetaboLights
MetabolomicsCharacterization of the heat-stable proteome during seed germination in Arabidopsis with special focus on LEA proteins
During seed germination, desiccation tolerance is lost in the radicle with progressing radicle protrusion and seedling establishment. This process is accompanied by comprehensive changes of the metabolome and proteome. Germination of Arabidopsis seeds was investigated over 72 h with special focus on...
2021-07-29 | MTBLS2980 | MetaboLights
ModelsUhlén2015 - Human tissue-based proteome metabolic network - small intestine
Uhlén2015 - Human tissue-based proteome metabolic network - small intestine Human small intestine specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P,...
2015-01-28 | MODEL1411240024 | BioModels
ProteomicsSerum Small Extracellular Vesicles Proteome of Tuberculosis Patients Demonstrated Deregulated Immune Response.
Detailed understanding of host pathogen interaction in tuberculosis is an important avenue for identifying novel therapeutic targets. Small extracellular vesicles (EVs) like exosomes are rich in proteins, nucleic acids and lipids, act as messenger and may show altered composition in disease conditio...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-05-29 | MSV000082412 | MassIVE
ProteomicsExploring the hidden world of Methanosarcina mazei: Unravelling the secrets of its small proteome and its nitrogen-dependent regulation
The mesophilic methanogenic archaeal model organism Methanosarcina mazei strain Gö1, is crucial for climate and environmental research due to its ability to produce methane from H2 plus CO2, acetate, and methylamines. Here, we established the first Ribo-seq protocol for M. mazei strain Gö1 under two...
ORGANISM(S): Methanosarcina mazei Go1 
2024-08-02 | PXD045039 | Pride
Archaea  methanoarchaea  ribosome profiling  ribo-seq  small proteome  sorf  nitrogen  dual function srna 
ProteomicsReanalysis of Pandey lab's draft of the human proteome
The availability of human genome sequence has transformed biomedical research over the past decade. However, an equivalent map for the human proteome with direct measurements of proteins and peptides was lacking. To this end, Akhilesh Pandey's lab reported a draft map of the human proteome based on...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-PROT-1 | biostudies-arrayexpress
GenomicsNon-small cell lung cancer proteome subtypes expose targetable oncogenic drivers and immune evasion mechanisms
Proteome-level data of non-small cell lung cancer remains limited. In this study, we have collected 141 cases, and performed histological review, methylation profiling (113), custom panel sequencing (140), microarray expression profiling (118) and mass-spectrometry based proteomics (141). We identif...
EGAS00001005482 | EGA
ProteomicsSmall Proteome of Haloferax volcanii - reference genome proteins.
The small proteome has already been well explored in eukaryal and bacterial species, but so far, archaeal genomes have not yet been analysed broadly with a dedicated focus on small proteins. Here, we present a combinatorial approach, integrating experimental information from small protein-optimized ...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) 
2023-02-01 | PXD031423 | Pride
Sep Archaea Sprotein Proteogenomics Database search Sorf Small protein enrichment Top-down Ribosome profiling Haloferax volcanii Small protein Proteolytic digest 
TranscriptomicsComparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment (small airway epithelial cells-microRNA dataset)
The biological impact of an aerosol of a potential modified-risk tobacco product, carbon heated tobacco product 1.2 (CHTP1.2), was comprehensively assessed for the first time in vitro using human small airway and nasal epithelial models following a systems toxicology approach. The potentially reduce...
ORGANISM(S): Homo sapiens 
2018-01-04 | E-MTAB-6611 | biostudies-arrayexpress
ProteomicsAn Optimised Proteomics Workflow for the Detection of Small Proteins.
Small open reading frame encoded proteins (SEPs) gained increasing interest during the last years due to their broad range of important functions in both, prokaryotes and eukaryotes. In bacteria, signalling, virulence or regulation of enzyme activities have been associated with SEPs. Nonetheless, th...
ORGANISM(S): Bacillus Subtilis 
2020-09-08 | PXD020514 | panorama
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