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MetabolomicsSericin Enhances Cryopreserved Sperm Quality in Chengde Hornless Black Goats by increasing Glutamine metabolism

Cryopreservation of Chengde polled goat semen plays a critical role in conserving genetic resources, enhancing the utilization efficiency of superior breeding rams, and advancing artificial insemination techniques. However, spermatozoa are vulnerable to oxidative stress during the freezing proces...

2025-08-15 | MTBLS12860 | MetaboLights
MetabolomicsA new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics

BACKGROUND: Semen quality is negatively correlated with male age and is mainly quantified by a routine semen analysis, which is descriptive and inconclusive. Sperm proteins or semen metabolites are used as the intermediate or end-products, reflecting changes in semen quality, an...

2024-01-16 | MTBLS5289 | MetaboLights
ProteomicsMouse Sperm TMT MCP
Mouse Sperm Proteomic Profiling - University of Newcastle - Dr. Matt Dun
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-06-24 | MSV000082497 | MassIVE
ProteomicsComparative proteomic and phosphorylated proteomic analyses revealed differences in sperm motility in Mediterranean buffalo
In this study, Mediterranean buffalo semen was used as experimental material, and quantitative proteomics and phosphorylation modification techniques were used to analyze the proteins and phosphorylation sites of Mediterranean buffalo sperm with different motility, so as to further study the protein...
ORGANISM(S): Bos Taurus 
PXD055618 |
ProteomicsCrocodile Sperm Proteome
In a reproductive strategy that is considered unique to the mammalian lineage, spermatozoa must undergo a series of physiological changes, termed capacitation, in the female reproductive tract prior to developing their capacity to fertilize an ovum. Here, we have employed a comparative proteomic str...
ORGANISM(S): Crocodylus Porosus (ncbitaxon:8502) 
2018-04-08 | MSV000082258 | MassIVE
ProteomicsBovine sperm surface lectinome
Identification of bovine sperm surface carbohydrate-binding proteins relevant in two important aspects of fertilization: (i) formation of the sperm reservoir in the oviductal epithelium, and (ii) gamete recognition (oocyte-sperm interaction). Using whole sperm cells and a novel affinity capture meth...
ORGANISM(S): Bos taurus (Bovine) 
2016-04-28 | PXD003386 | Pride
Bovine Sperm Lectins Fertilization 
ProteomicsSperm proteome of apyrene and eupyrene sperm in Carolina Sphinx moth Manduca sexta, and monarch butterfly Danaus plexippus
All but the most basal Lepidopteran species produce two sperm morphs. Only one of these morphs is capable of completing karyogamy and producing offspring, this morph contains the correct genetic complement and is termed eupyrene sperm. Apyrene sperm, on the other hand, is completely devoid of nucle...
ORGANISM(S): Danaus plexippus Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) 
2019-05-06 | PXD010168 | Pride
Monarch Manduca sexta Sperm heteromorphism Lepidoptera Sperm 
ProteomicsThe reproductive toxicant acrylamide modulates the mouse epididymal proteome to drive alterations to the sperm epigenome and dysregulate embryo development.
Paternal exposure to a range of environmental and lifestyle factors elicits distinct changes to the sperm sncRNA profile; modifications that have significant post-fertilization consequences. Despite this knowledge, there remains limited mechanistic understanding of how paternal exposures effect the ...
ORGANISM(S): Mus Musculus 
2021-10-08 | PXD022876 | panorama
ProteomicsAstral-DIA Proteomics Deciphers the Molecular Landscape of Human Spermatozoa: A Comprehensive Quantitative Proteomic Characterization of Sperm Function and Fertility Potential
Male infertility is fundamentally rooted in developmental defects of germ cells and associated molecular dysregulation, yet the underlying mechanisms remain poorly understood. Data-independent acquisition (DIA) has emerged as a powerful tool in discovery proteomics, enabling the identification of di...
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD061638 | Pride
Astral-dia  proteomics  human spermatozoa  sperm function 
ProteomicsIdentification of key genes related to sperm freezability in Holstein bulls using proteomics and association analysis
We compared protein profiles of sperm cells in the high sperm freezability group and the low sperm freezability group of Holstein bulls to identify the important proteins and their mechanisms that affect sperm freezability.
ORGANISM(S): Bos taurus (Bovine) 
2026-02-23 | PXD053574 | Pride
Sperm Proteome Freezability 
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