Mass spectrometry-based proteomic analysis of A7r5 rat smooth muscle cells subject to uniaxial cyclic stretching, in the presence or absence of the autophagy inhibitor Chloroquine.
To study the effects of mechanical stretching on fibroblasts, two cell lines, HFF and KF, were subject to 50% uniaxial mechanical stretching for 6, 12, and 18 hours, followed by RNA-seq.
Morphology together with the capability to respond to surrounding stimuli are the key elements governing the spatial interaction of a living cell with the environment. In this respect, biomechanical stimulation can trigger significant physiological cascades that can potentially modulate or interact ...
