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MetabolomicsViral infection of algal blooms leaves a unique metabolic footprint on the dissolved organic matter in the ocean

Algal blooms are hotspots of primary production in the ocean, forming the basis of the marine food web and fueling the dissolved organic matter (DOM) pool. Marine viruses are key players in controlling algal bloom demise, thereby diverting algal biomass from higher trophic levels to the DOM pool,...

2021-05-05 | MTBLS1720 | MetaboLights
GenomicsLarge-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients
Despite the high global prevalence of chronic hepatitis B (CHB) infection, datasets covering the whole hepatitis B viral genome from large patient cohorts are lacking, greatly limiting our understanding of the viral genetic factors involved in this deadly disease. We performed deep sequencing of vir...
EGAS00001003689 | EGA
ProteomicsTARA Oceans Viral Proteins - Illuminating structural proteins in viral "dark matter" with metaproteomics
A grand challenge in biology is the lack of annotation for much of global sequence space. In particular, while microbes and their viruses are critical to Earth System functioning, surveys of their communities in nature routinely return genes of unknown function, particularly for viruses. This hamper...
ORGANISM(S): environmental samples 
2016-02-25 | PXD000938 | Pride
Viral proteomics Virus Tara Viral Proteomics Proteins 
TranscriptomicsStructural basis for retroviral integration into nucleosomes
Retroviral integration is catalyzed by a tetramer of integrase (IN) assembled on viral DNA ends in a stable complex, known as the intasome. How the intasome interfaces with chromosomal DNA, which exists in the form of nucleosomal arrays, is currently unknown. Here we show that the prototype foamy vi...
ORGANISM(S): Homo sapiens 
2015-06-10 | E-GEOD-67730 | biostudies-arrayexpress
TranscriptomicsSmall RNA from S2 cell infected with FHV deltaB2 particle
S2 cells were infected with FHV deltaB2 particle and the S2 cells were harvested to isolate total RNA at 96 hpi. Small RNAs were separated on a denaturing 15% polyacrylamide gel. Ligation to adapters requires 5' monophosphate and 3' OH. Note: The base quality (.qual) file corresponding to the fasta...
ORGANISM(S): Drosophila melanogaster 
2008-10-15 | E-GEOD-12527 | biostudies-arrayexpress
TranscriptomicsIMR90 bystander experiment 0.5 Gy alpha particle
The existence of a radiation bystander effect, in which non-irradiated cells respond to signals from irradiated cells, is well established. It raises concerns for the interpretation of risks from exposure to low doses of ionizing radiation. Sparse data exists about the bystander signaling mechanisms...
ORGANISM(S): Homo sapiens 
2010-07-21 | E-GEOD-18760 | biostudies-arrayexpress
ProteomicsShotgun proteomics of Vero E6 cells infected by Italy-INMI1 SARS-CoV-2 virus
Next-generation proteomics of Vero E6 cells infected by Italy-INMI1 SARS-CoV-2 virus for defining the kinetics of whole viral particle antigen production for vaccines. Cells from Day1, Day2, Day3, Day4, Day7 post-infection at two multiplicities of infection.
ORGANISM(S): Chlorocebus aethiops aethiops Betacoronavirus sp. 
2020-06-03 | PXD018594 | Pride
Viral particle Virus Severe acute respiratory syndrome Sars-cov-2 Coronavirus Vaccine Host response Covid-19 Kinetics 
ProteomicsGeneration and utilization of a monoclonal antibody against hepatitis B virus core protein for a comprehensive interactome analysis
Hepatitis B virus (HBV) core antigen (HBc) is a structural protein that forms the viral nucleocapsid and is involved in various steps of the viral replication cycle, but its role in the pathogenesis of HBV infection is still elusive. In this study, we generated a mouse monoclonal antibody against HB...
ORGANISM(S): Homo Sapiens (human) 
2023-02-21 | PXD036961 | JPOST Repository
ProteomicsLC-MS/MS analyses of purified virions of influenza A and B viruses, grown in a range of hosts.
LC-MS/MS analyses of purified virions of influenza A and B viruses, grown in a range of hosts. Described in Hutchinson et al. 'Conserved and host-specific features of influenza virion architecture.'
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Canis Familiaris (canine) Influenza Viruses Gallus Gallus (ncbitaxon:9031) 
2014-06-16 | MSV000078740 | MassIVE
ProteomicsProteomics analysis of viral infection in neurons
Endemic viral infections with low pathogenicity are often overlooked due to their mild symptoms, yet they can exert long-term effects on cellular function and contribute to disease pathogenesis. While viral infections have been implicated in neurodegenerative disorders, their impact on the neuronal ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-23 | PXD061286 | Pride
Virus Ipsc-derived neurons 
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