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Resting platelets isolated from adult and postnatal day 7 (p7) C57BL/6J mice. We used DDA mass spectrometry to analyze the whole proteome from these samples.
ORGANISM(S): Mus musculus (Mouse) 
2026-01-29 | PXD071601 | Pride
Mutations in tRNAs can lead to mis-incorporation of an amino acid into a growing polypeptide chain that differs from what is specified by the mRNA in a process known as mistranslation. As mistranslating tRNAs modify how the genetic message is decoded, they have potential as therapeutic tools to trea...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-11-18 | PXD068392 | Pride
Navtemadlin is a potent small moeclule inhibitor of the p53-MDM2 protein-protein interaction, that is being tested in Phase II/III clinical trials for the treatment of cancer. The selectivity of this molecule is poorly understood. So we synthesised and validated two photoactivatable clickable probes...
ORGANISM(S): Homo sapiens (Human) 
2025-04-28 | PXD058050 | Pride
Navtemadlin is a potent small moeclule inhibitor of the p53-MDM2 protein-protein interaction, that is being tested in Phase II/III clinical trials for the treatment of cancer. The selectivity of this molecule is poorly understood. So we synthesised and validated two photoactivatable clickable probes...
ORGANISM(S): Homo sapiens (Human) 
2025-04-28 | PXD058047 | Pride
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