Sort   by:  
 Page size 
ProteomicsQuantitative proteomes of Imp2 KO mouse 2-cell-stage embryos
Data showing the late 2-cell-stage, control embryos (Imp2♀+/♂+) and Imp2-knockout embryos (Imp2♀−/♂+) for HPLC MS/MS analysis. 3 replicates were performed using 330 embryos per group.
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD010397 | Pride
Imp2 Tmt Quantitative 2-cell-stage embryos 
Proteomics,Multiomicsembryo_proteome
We collected over 8000 mouse embryos of each developmental stage (zygote, 2-cell, 4-cell, 8-cell, morula, blastocyst) and performed tandem mass tag (TMT)-based quantitative mass spectrometry and identified nearly 5000 proteins for each stage. In-depth analysis indicates that protein expression profi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-12-10 | MSV000079417 | MassIVE
TranscriptomicsSingle-cell RNA-seq of blastomeres from 2- to 32-cell stage mouse embryos
Transcriptomes were determined for all blastomeres of 28 embryos at the 2- (n=8), 4- (n=16) and 8-cell (n=4) stages, and for individual cells taken from 16- (n=6) and 32- (n=6) cell stage embryos. We also carefully monitored the 2- to 4-cell divisions noting whether the cleavage plane was meridional...
ORGANISM(S): Mus musculus 
2016-03-23 | E-MTAB-3321 | biostudies-arrayexpress
TranscriptomicsThe DNA methylation landscape of human early embryos
Our data provided a genome-wide DNA methylation landscape of human early development embryos, including human MII oocytes, sperm, zygotes, 2-cell to 8-cell embryos, morula, blastocyst and postimplantation embryos at single base resolution. In total, 44 samples including biological and technical repl...
ORGANISM(S): Homo sapiens 
2014-07-22 | E-GEOD-49828 | biostudies-arrayexpress
GenomicsSingle-cell RNA-seq of blastomeres from 2- to 32-cell stage mouse embryos
Single-cell RNA-seq of blastomeres from 2- to 32-cell stage mouse embryos
PRJEB12525 | ENA
ProteomicsSingle cell analysis for oocytes and early embryos
While non-mammalian embryos often rely on spatial pre-patterning, for decades it was believed that blastomeres of mouse and human embryos were developmentally equivalent. However, emerging evidence suggests early mouse and human blastomeres differ in developmental potential. Here, using multiplexed ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2025-08-10 | MSV000098778 | MassIVE
TranscriptomicsGene expression analysis of eight-cell stage rat embryos sired by paternally exposed males to saline or BEP
8-cell stage rat embryos were sired by males treated with saline or a chemotherapeutic cocktail, BEP, consisting of Bleomycin, Etoposide, and Cisplatin for 9 weeks. Animals were given an additional 9 weeks of recovery, without any treatment, prior to mating. qPCR gene expression profiling for 84 ste...
ORGANISM(S): Rattus norvegicus 
2014-03-13 | E-GEOD-55842 | biostudies-arrayexpress
TranscriptomicsTranscript profiling of individual twin blastomeres derived by splitting 2-cell stage murine embryos
We have examined whether twin blastomeres from 2-cell stage mouse embryos differ in mRNA content. Amplified mRNA from 12 blastomeres derived from six embryos approximately mid-way through their second cell cycle was analyzed. Probes displaying normalized values greater than 0.25 were selected and ex...
ORGANISM(S): Mus musculus 
2010-05-28 | E-GEOD-21688 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiles in Oct4-knockdown and Ccna2-knockdown mouse embryos.
Gene regulation at the maternal-embryonic transition in the pre-implantation mouse embryo is not well understood. We knock down Ccna2 to establish proof-of-concept that antisense morpholino oligonucleotides can be used to target specific genes. We applied this strategy to study Oct4 and discovered...
ORGANISM(S): Mus musculus 
2008-12-30 | E-GEOD-13981 | biostudies-arrayexpress
GenomicsscRNA-Seq of Phallusia mammillata from 2-cell to 16-cell stage
scRNA-Seq of Phallusia mammillata from 2-cell to 16-cell stage
PRJEB25096 | ENA
Sort   by:  
 Page size