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TranscriptomicsA Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-mediated mRNA Translation
Increasing evidence suggests that Long non-coding RNAs (LncRNAs) represent a new class of regulators of stem cells. However, the roles of LncRNAs in stem cell maintenance and myogenesis remain largely unexamined. For this study, hundreds of novel intergenic LncRNAs were identified that are expresse...
ORGANISM(S): Mus musculus 
2015-08-11 | E-GEOD-68842 | biostudies-arrayexpress
TranscriptomicsIGF2BP2/IMP2 Deficient Mice Resist Obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding Mitochondrial Proteins
Imp2 -/- mice were subjected to a number of characterization assays, including RNA-Seq of various tissues, Characterization of IMP2 -/- mice including various metabolic measurements.
ORGANISM(S): Mus musculus 
2015-03-03 | E-GEOD-66440 | biostudies-arrayexpress
TranscriptomicsIMP2/IGF2BP2 HITS-CLIP from E13.5 mouse brain
HITS-CLIP is performed for the RNA-binding protein, IMP2/IGF2BP2, from E13.5 mouse brain.
ORGANISM(S): Mus musculus 
2016-06-06 | E-MTAB-3636 | biostudies-arrayexpress
TranscriptomicsIMP2 axonal localization, RNA interactome, and function in development of axon trajectories
RNA-based regulatory mechanisms play important roles in the development and plasticity of neural circuits and neurologic disease. Developing axons provide a well suited model to study RNA-based regulation, and contain specific subsets of mRNAs that are locally translated and have roles in axon pathf...
ORGANISM(S): Mus musculus 
2016-08-02 | E-GEOD-83822 | biostudies-arrayexpress
ProteomicsStructural insights into IMP2 dimerization and RNA binding
IGF2BP2 (IMP2) is an RNA binding protein contributing to tumorigenesis across various cancers as well as to metabolic disorders. With the growing interest in drug discovery efforts targeting IMP2, an understanding of its structural properties and biological behavior are needed. Thus far, only partia...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD049065 | Pride
Imp2 Hdx-ms 
GenomicsIMP2-TRIBE
Detection of IMP2 binding sites
PRJEB71750 | ENA
ProteomicsQuantitative proteomes of Imp2 KO mouse 2-cell-stage embryos
Data showing the late 2-cell-stage, control embryos (Imp2♀+/♂+) and Imp2-knockout embryos (Imp2♀−/♂+) for HPLC MS/MS analysis. 3 replicates were performed using 330 embryos per group.
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD010397 | Pride
Imp2 Tmt Quantitative 2-cell-stage embryos 
GenomicsNext Generation Sequencing (NGS) analysis of mice pancreatic islets from control and IMP2 islet specific knockout (Rip2 IMP2).
Next Generation Sequencing (NGS) analysis of mice pancreatic islets from control and IMP2 islet specific knockout (Rip2 IMP2).
PRJNA639283 | ENA
GenomicsIMP2/IGF2BP2 HITS-CLIP from E13.5 mouse brain
IMP2/IGF2BP2 HITS-CLIP from E13.5 mouse brain
PRJEB9614 | ENA
GenomicsEffect of IMP2 overexpression in murine liver
Transgenic expression of the RNA binding protein IMP2 stabilizes miRNA targets in murine microsteatosis
PRJEB21164 | ENA
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