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Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
ProteomicsProteomic analysis of Caenorhabditis elegans wound model reveals novel molecular players involved in repair
Now a days, wound healing is becoming a global threat that impact economy of the country severely. Though the steps involved in wound healing are well characterised, direct therapeutics for the accelerated wound healing is comparatively less. This is solely because of the incomplete mechanism of hea...
ORGANISM(S): Caenorhabditis elegans 
2021-04-16 | PXD024629 | Pride
C. elegans 2-d ge Whole body Injury 
TranscriptomicsLMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression
The mRNA processing body is a cellular structure that regulates the stability of cytoplasmic mRNA. MARF1/LMKB is an RNA-binding protein that is associated with maintenance of mRNA homeostasis and genomic stability. To investigate the function of LMKB in a human B lymphocyte cell line, BJAB cells w...
ORGANISM(S): Homo sapiens 
2014-06-09 | E-GEOD-55974 | biostudies-arrayexpress
no omics definedTranscription profiling of human acute myeloid leukemia cells to identify compounds inducing the differentiation of acute myeloid leukemia cells
We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute ...
ORGANISM(S): Homo sapiens 
2007-09-20 | E-GEOD-995 | biostudies-arrayexpress
TranscriptomicsRNAi knock down of mRNA decapping co-activators in Drosophila S2 cells
We analyzed mRNA expression profiles in Drosophila melanogaster S2 cells that had been depleted of proteins known as mRNA decapping co-activators. mRNA decapping is catalyzed by DCP2, and DCP2 activity is stimulated by decapping co-activators. This group of proteins includes DCP1, Hedls (also known ...
ORGANISM(S): Drosophila melanogaster 
2007-09-03 | E-MEXP-1012 | biostudies-arrayexpress
UnknownDevelopment & automation of a novel [(18)F]F prosthetic group, 2-[(18)F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide.
Not available
S-EPMC5034901 | biostudies-literature
TranscriptomicsExpression profiling of luminal and glandular epithelia in the neonatal and adult mouse uterus
Laser capture microdissection coupled with microarray genes expression analysis were utilized in order to elucidate the regulatory networks active in epithelial cells of the neonatal and adult mouse uterus. Genes predominantly expressed in the glandular epithelium (GE) in the neonatal or adult uteru...
ORGANISM(S): Mus musculus 
2013-11-05 | E-GEOD-48239 | biostudies-arrayexpress
UnknownFirst Organic-Inorganic Hybrid Compounds Formed by Ge-V-O Clusters and Transition Metal Complexes of Aromatic Organic Ligands.
Not available
S-EPMC9323094 | biostudies-literature
UnknownMolecular Ln(III)-H-E(II) Linkages (Ln=Y, Lu; E=Ge, Sn, Pb).
Not available
S-EPMC9541956 | biostudies-literature
TranscriptomicsComparative transcriptomic profiling of peripheral blood mononuclear cells (PBMNCs) isolated from pigs exposed to an atherogenic diet (AD) or to an AD supplemented with Grape Extract (GE) and/or Resveratrol (RES).
We used Affymetrix microarrays to investigate gene expression changes in PBMNCs isolated from female and male pigs to determine significant modulatory effects that may have been induced by the intake of GE and (or) RES during 4 months in animals fed an atherogenic diet (AD) . The aim of this work wa...
ORGANISM(S): Sus scrofa 
2011-07-22 | E-GEOD-30874 | biostudies-arrayexpress
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