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ProteomicsValidation and invalidation of chemical probes for the human N-myristoyltransferases.
On-target, cell-active chemical probes are of fundamental importance in both chemical and cell biology, whereas the application of poorly-characterised probes often leads to invalid conclusions. Human N-myristoyltransferase (NMT) has attracted increasing interest as a target in cancer and infectious...
ORGANISM(S): Homo sapiens (Human) 
2019-11-14 | PXD012722 | Pride
N-myristoylation Imp-366 (ddd85646) Metabolic tagging Tris-dba palladium Myristic acid alkyne ynmyr Chemical proteomics Imp-1088 D-nmappd (b13) 2-hydroxymyristic acid 
UnknownThe structure of LpxD from Pseudomonas aeruginosa at 1.3 A resolution.
Not available
S-EPMC3144788 | biostudies-literature
UnknownPresence of 2-hydroxymyristate on endotoxins is associated with death in neonates with Enterobacter cloacae complex septic shock.
Not available
S-EPMC8361193 | biostudies-literature
UnknownValidation and Invalidation of Chemical Probes for the Human N-myristoyltransferases.
Not available
S-EPMC6593224 | biostudies-literature
UnknownEvaluation of Cytotoxicity and Metabolic Profiling of Synechocystis sp. Extract Encapsulated in Nano-Liposomes and Nano-Niosomes Using LC-MS, Complemented by Molecular Docking Studies.
Not available
S-EPMC11351938 | biostudies-literature
MetabolomicsCyclobutene- and cyclobutane-functionalized fatty acids as novel biochemical probes of structure and function in HepG2 cells
Not available
ORGANISM(S): Homo sapiens 
ST000241 | MetabolomicsWorkbench
MetabolomicsEvidence that the metabolite repair enzyme NAD(P)HX epimerase has a moonlighting function
Not available
ORGANISM(S): Escherichia coli 
ST000900 | MetabolomicsWorkbench
MetabolomicsDownregulation of CENPF epigenetically remodels prostate cancer cells and alters cellular metabolism
Not available
ORGANISM(S): Homo sapiens 
ST001133 | MetabolomicsWorkbench
MetabolomicsMetabolomic and Cultivation Insights into the Tolerance of the Spacecraft-Associated Acinetobacter Towards Kleenol 30, a Cleanroom Floor Detergent
Not available
ORGANISM(S): Acinetobacter 
ST002380 | MetabolomicsWorkbench
MetabolomicsMaternal obesity alters offspring liver and skeletal muscle metabolism in early post-puberty despite maintaining a normal post-weaning dietary lifestyle
Not available
ORGANISM(S): Papio hamadryas 
ST002254 | MetabolomicsWorkbench
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