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Proteins can be modified by lipids in various ways, for example by myristoylation, palmitoylation, farnesylation, and geranylgeranylation—these processes are collectively referred to as lipidation. Current chemical proteomics using alkyne lipids has enabled the identification of lipidated protein ca...
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
Inhibition of protein N-myristoylation blocks Plasmodium falciparum intracellular development and egress, but myristoylation of GAP45 is required only for erythrocyte invasion. TMT quantification used to determine protein expression changes upon inhibition of myristoylation
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-10-07 | PXD021879 | Pride
Inhibition of host N-myristoylation compromising the infectivity of SARS-CoV-2 due to Golgi-bypassing egress
In this project, the aim was to investigate the effect of NMT inhibition during schizogony, synchronized parasite populations.
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2021-10-07 | PXD022704 | Pride
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