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Two-dimensional (2D) liquid chromatography (LC)-tandem mass spectrometry (MS/MS) are typically employed for deep bottom-up proteomics, and the state-of-the-art 2D-LC-MS/MS has approached over 8,000 protein identifications (IDs) from mammalian cell lines or tissues in 1-3 days of mass spectrometer ti...
ORGANISM(S): Mus musculus (Mouse) 
2018-02-27 | PXD008432 | Pride
Recent advances in mass spectrometric (MS) instruments resulting in high mass resolution and high duty cycles have allowed of very deep coverage of proteomes. However, even with state of the art, high duty cycle instruments, the number of proteins identified with a conventional single liquid chromat...
ORGANISM(S): Homo sapiens (Human) 
2018-04-23 | PXD009021 | Pride
Proteome profile of MCF7 breast cancer cells stimulated with insulin and analyzed by nano-LC-ESI-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2016-11-30 | PXD004051 | Pride
A deeper understanding of malaria parasite development inside the Anopheles mosquito may lead to the identification of processes that can be targeted by transmission-blocking interventions. Paraquat (1,1'-dimethyl-4,4'-bipyridylium dichloride) is a potent superoxide-inducing agent that impacts Plasm...
ORGANISM(S): Anopheles gambiae (African malaria mosquito) 
2022-03-01 | PXD008231 | Pride
We found the ratio of substrate depletion is independent of other coexisted substrates under specific condition with the application of self-developed iteration approach. The further established simplified model was applied to determine the catalytic efficiencies of peptide substrates of a protease ...
ORGANISM(S): Homo sapiens (Human) 
2017-02-08 | PXD004665 | Pride
Duck Tembusu virus (DTMUV) is a newly emerging pathogenic flavivirus that has caused huge economic losses to the duck industry in China since 2010. Moreover, DTMUV can also infect geese, chickens, house sparrows and replicate in in the brain, spleen, liver and kidneys of BALB/c mice, which poses pub...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2017-05-23 | PXD005731 | Pride
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