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Unknown(E)-3-[(Di-methyl-amino)-methyl-idene]-4-phenyl-1H-1,5-benzodiazepin-2(3H)-one.
Not available
S-EPMC3998293 | biostudies-literature
Unknown1-[2-(2-Oxo-1,3-oxazolidin-3-yl)eth-yl]-4-phenyl-1H-1,5-benzodiazepin-2(3H)-one.
Not available
S-EPMC3007442 | biostudies-literature
Unknown(E)-3-[(Di-methyl-amino)-methyl-idene]-4-phenyl-1-(prop-2-yn-yl)-1H-1,5-benzodiazepin-2(3H)-one.
Not available
S-EPMC3914077 | biostudies-literature
TranscriptomicsEffects of diazepam on gene expression and link to physiological effects in different life stages in zebrafish Danio rerio
We applied zebrafish whole genome microarrays to identify molecular effects of diazepam, a neuropharmaceutical encountered in wastewater-contaminated environments, and to elucidate its neurotoxic mode of action. Behavioral studies were performed to analyze for correlations between altered gene expre...
ORGANISM(S): Danio rerio 
2011-07-22 | E-GEOD-23157 | biostudies-arrayexpress
Unknown1,5-Benzodiazepin-2(3H)-ones: In Vitro Evaluation as Antiparkinsonian Agents.
Not available
S-EPMC8533176 | biostudies-literature
ProteomicsA proteomic platform unveils the brain glycogen phosphorylase as a potential metabolic target for glioblastoma multiforme
In the last few years, several efforts have been ended to identify original strategies against gli-oblastoma multiforme (GBM): this requires a more detailed investigation of the molecular mechanism of GBM so that novel targets can be identified for new possible therapeutic agents. Here, using a combi...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD034933 | Pride
3-benzodiazepin-4-one Glycogen phosphorylase Proteomics 2 Target identification Glioblastoma multiforme 
UnknownMechanism of inhibition of GluA2 AMPA receptor channel opening by 2,3-benzodiazepine derivatives: functional consequences of replacing a 7,8-methylenedioxy with a 7,8-ethylenedioxy moiety.
Not available
S-EPMC3329945 | biostudies-literature
UnknownDual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety.
Not available
S-EPMC2957775 | biostudies-literature
TranscriptomicsGene expression profiles of non-genotoxic hepatocarcinogens and hepatotoxicants in rat liver
Liver tumors in rodents are frequently induced by non-genotoxic carcinogens. These hepatocarcinogens generally activate hepatic nuclear receptors (e.g., CAR and PXR), resulting in a cascade of signals causing modifications in the expression of genes responsible for several processes involved in carc...
ORGANISM(S): Rattus norvegicus 
2013-07-31 | E-GEOD-39350 | biostudies-arrayexpress
TranscriptomicsHippocampal neuronal dematuration as a common effect of antidepressant treatments
The dentate gyrus (DG) of the hippocampus is one of major targets for antidepressant treatments. Our recent research has revealed that selective serotonin reuptake inhibitor (SSRI) treatment causes a long-lasting change in the phenotypes of mature dentate granule neurons to immature state in adult m...
ORGANISM(S): Mus musculus 
2014-04-01 | E-GEOD-54307 | biostudies-arrayexpress
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