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TranscriptomicsMolecular variability of FLT3/ITD mutants and their impact on the differentiation program of 32D cells
FLT3 is the most frequently mutated gene in AML – up to 40% of AML harbor an activating mutation within FLT3 gene. Though AML is a relatively rare disease, such a high mutability rate, as observed with FLT3 gene, is striking. To elucidate the molecular background of this phenomenon, we have establ...
ORGANISM(S): Mus musculus 
2010-04-08 | E-GEOD-12766 | biostudies-arrayexpress
TranscriptomicsGenes Differentially Expressed as a Result of Enforced EDAG Expression In 32D Cells
Erythroid differentiation-associated gene (EDAG), a hematopoietic tissue-specific transcription regulator, plays a key role in maintaining the homeostasis of hematopoietic lineage commitment. However, the mechanism and genes regulated by EDAG remain unknown.Here, we performed genome-wide parallel ex...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-18862 | biostudies-arrayexpress
TranscriptomicsOverexpression of miR-9 and miR-9* in 32D cells
Overexpression of miR-9 and miR-9* in 32D cells, cells grown under IL-3 conditions and miR-9 and miR-9* were introduced with retroviral vectors containing about ~150 bp up and downstream of mmu-mir-9-2. Expression was determined to find out the effect of miR-9/9*overexpression on the transcriptome l...
ORGANISM(S): Mus musculus 
2012-11-01 | E-GEOD-41942 | biostudies-arrayexpress
ProteomicsG-CSF mediated signalling in 32D cells
G-CSF signalling has been extensively characterized in myeloid progenitor cells but the activation dynamics downstream of the receptor at different stages of cell differentiation in wild-type G-CSFR or in proliferating cells that harbor the d715 mutation has not been been investigated at the phospho...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-22 | PXD026317 | Pride
Tmt 32d Phosphoproteom Proteome 
ProteomicsSWATH-proteomics analysis of ibrutinib mechanism of action in neutropenia and acute myeloid leukemia initiating mutated granulocyte-colony stimulating factor receptor
Neutrophil production and function are primarily determined by granulocyte colony stimulating factor receptor (G-CSFR). G-CSFRs associated mutations (mostly localized in the transmembrane and cytoplasmic domains of the receptor) have been reported with several distinct hematological abnormalities as...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-27 | PXD013402 | Pride
Btk inhibitor Swath 32d G-csfr 
GenomicsThe Nup98::Nsd1 fusion gene induces CD123 expression in 32D cells
The Nup98::Nsd1 fusion gene induces CD123 expression in 32D cells
PRJNA893565 | ENA
GenomicsGenome-wide C/ebpβ and Jmjd3 traget genes in 32D cells.
To characterize genome-wide C/ebpβ and Jmjd3 traget genes in 32D cells by ChIP-seq.
ORGANISM(S): Mus musculus 
2018-06-13 | GSE100487 | GEO
UnknownParadoxical counteraction by imatinib against cell death in myeloid progenitor 32D cells expressing p210BCR-ABL.
Not available
S-EPMC6114964 | biostudies-literature
UnknownA novel cold-active β-D-galactosidase from the Paracoccus sp. 32d--gene cloning, purification and characterization.
Not available
S-EPMC3268748 | biostudies-literature
GenomicsRNA sequencing of 32D clone 3 cells transfected with CXCR2 (pEGFP-N1-CXCR2) or an empty vector(pEGFP-N1)
RNA sequencing of 32D clone 3 cells transfected with CXCR2 (pEGFP-N1-CXCR2) or an empty vector(pEGFP-N1)
PRJNA515898 | ENA
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