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ProteomicsPhosphoproteom of Cashmere goat fetal fibroblast（LC-MS/MS）
This study examined differences in the phosphorylation levels of proteins in response to amino acid signals in Cashmere goat fetal fibroblasts.
ORGANISM(S): Capra hircus (Goat) 
2021-08-06 | PXD025488 | Pride
Goat phosphoproteom amino acid lc-ms/ms 
ProteomicsExtensive arginine phosphorylation in Staphylococcus aureus is influences by Stp1
Ever since the identification of the first protein-arginine kinase, McsB, in B. subtilis arginine phosphorylation gained more attention. However, the analysis of phosphorylations especially phosphormaidates comes along with several challenges. The sub-stoichiometric nature of protein phosphorylation...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 Escherichia coli Staphylococcus aureus 
2022-06-09 | PXD026981 | Pride
Fragmentation Staphylococcus aureus Stp1 Phosphorylation Arginine phosphorylation 
ProteomicsG-CSF mediated signalling in 32D cells
G-CSF signalling has been extensively characterized in myeloid progenitor cells but the activation dynamics downstream of the receptor at different stages of cell differentiation in wild-type G-CSFR or in proliferating cells that harbor the d715 mutation has not been been investigated at the phospho...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-22 | PXD026317 | Pride
Tmt 32d Phosphoproteom Proteome 
ProteomicsActivation of hypothalaActivation of hypothalamic-enhanced adult-born neurons is sufficient to restore cognitive and noncognitive function in Alzheimer's diseasemic-enhanced adult-born neurons is sufficient to restore cognitive and noncognitive function in Alzheimer's diseaseActivation of hypothalamic-enhanced adult-born neurons is sufficient to restore cognitive and noncognitive function in Alzheimer's disease
Patients with Alzheimer’s disease (AD) exhibit progressive memory loss, depression, and anxiety, accompanied by impaired adult hippocampal neurogenesis (AHN). Whether modulating AHN is sufficient to improve these cognitive and noncognitive symptoms in AD remains elusive. Here we report that chronic ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-08 | PXD034176 | Pride
Mouse Hippocampus Lc-ms Phosphoproteom 
ProteomicsNeocarzilin inhibits cancer cell proliferation via BST-2 degradation resulting in lipid raft trapped EGFR
Neocarzilin (NCA) is a natural product exhibiting potent anti-migratory as well as anti-proliferative effects. While the vesicle amide transport protein 1 (VAT-1) was previously shown to inhibit migration upon NCA binding, the molecular mechanisms responsible for impaired proliferation remained elus...
ORGANISM(S): Homo sapiens (Human) 
2024-11-26 | PXD050453 | Pride
Natural products Cancer Proteomics Antitumor agents Biological activity 
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