Enteroid-derived intestinal epithelial cell monolayers were grown to capture immature progenitor-cell-promoting conditions for 7 days and maturation towards an enterocyte fate for 4 days. 3D enteroids in organoids growth media (OGM) included as control for a stem-cell rich phenotype.
To investigate the effect of human norovirus infection on the trascriptome of intestinal enteroids in the presence of a Jak kinase inhibitor, Ruxolitinib
Human noroviruses, globally the main cause of viral gastroenteritis, show strain specific affinity for histo-blood group antigens (HBGA) and can successfully be propagated ex vivo in human intestinal enteroids (HIEs). HIEs established from jejunal stem cells of individuals with different ABO, Lewis ...
