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ProteomicsIntegrative proteomic profiling of ovarian cancer cell lines reveals precursor-cell associated proteins and functional status
A cell line representative of human high-grade serous ovarian cancer (HGSOC) should not only resemble its tumor of origin at the molecular level, but also demonstrate functional utility in pre-clinical investigations. Here we report the integrated proteomic analysis of 26 ovarian cancer cell lines, ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-30 | MSV000080814 | MassIVE
ProteomicsEstablishment of dimethyl labeling-based quantitative acetylproteomics in Arabidopsis
Protein acetylation, one of many types of post-translational modifications (PTMs), is involved in a variety of biological and cellular processes. In the present study, we applied both CsCl density gradient (CDG) centrifugation-based protein fractionation and a dimethyl-labelling-based 4C quantitativ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-03-14 | PXD006177 | Pride
Cscl density gradient (cdg) centrifugation Stable isotope dimethyl labelling Arabidopsis Squa-d Acetylproteomics 4c proteomic workflow Quantitative ptm proteomics 
ProteomicsDevelopment of in planta chemical cross-linking-based quantitative interactomics in Arabidopsis
An in planta chemical cross-linking-based quantitative interactomics (IPQCX-MS) workflow has been developed to investigate in vivo protein-protein interactions and alteration in protein structures in a model organism, Arabidopsis thaliana. A chemical cross-linker, azide-tag-modified disuccinimidyl p...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-08-14 | PXD008161 | Pride
Arabidopsis thaliana Ecl2 In planta quantitative interactomics Ipqcx-ms In vivo cross-linking 4c proteomic workflow 
ProteomicsProteomic analysis of differential anther development from sterile/fertile lines in Capsicum annuum L.
Background: Pepper (Capsicum annuum L.) is a major cash crop throughout the world. Male sterility is an important characteristic in crop species that leads to a failure to produce functional pollen, and it has crucial roles in agricultural breeding and the utilization of heterosis. Objectives: In t...
ORGANISM(S): Capsicum annuum 
2022-05-19 | PXD031331 | Pride
Male sterility  proteomic parallel reaction monitoring (prm) phytohormone  pepper (capsicum annuum l.) 
UnknownEstablishment of Dimethyl Labeling-based Quantitative Acetylproteomics in Arabidopsis.
Not available
S-EPMC5930405 | biostudies-literature
ProteomicsProteomic analysis of focal cerebral ischemia/reperfusion injury in rats
Stroke is a leading cause of mortality and long-term disability and ischemic stroke accounts for 87% of all strokes. Though timely recanalization of the occluded vessel is essential in the treatment of ischemic stroke, it is well known to cause ischemia-reperfusion (I/R) injury which result in neuro...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-07-03 | PXD012151 | Pride
Middle cerebral artery occlusion (mcao) Proteomics Rat Time course Brain stroke Ischemia-reperfusion injury 
ProteomicsPROTEOMIC ANALYSIS OF EARLY DIABETIC RETINOPATHY REVEALS MEDIATORS OF NEURODEGENERATIVE BRAIN DISEASES
The aim of the present study was to identify early changes in diabetic retinas using an unbiased proteomics approach. Proteomic profiles of control retinas were compared to diabetic retinas obtained from patients known to have no classic vascular lesions that clinically define diabetic retinas. The ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD008989 | Pride
Human retina Diabetes 
ProteomicsHeart mitochondrial differential solubilisation in CHCD10 (S55L) and control mice
Mutations in CHCHD10, a mitochondrial protein implicated in proteostasis and cristae maintenance, cause autosomal dominant mitochondrial diseases characterized by cardiomyopathy and neurodegeneration. Heterozygous Chchd10 S55L knock-in mice (modeling the human S59L variant) develop progressive mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-07 | PXD064057 | Pride
Heart Mus musculus Mitochondria 
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Klebsiella pneumoniae complex
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia col...
ORGANISM(S): Klebsiella variicola Homo sapiens (Human) Klebsiella pneumoniae 
2021-07-05 | PXD016672 | Pride
Proteomics Rpmi Swath Klebsiella pneumoniae Sera Antibiotic resistance Sepsis 
ProteomicsTheft of Host Transferrin Receptor-1 by Toxoplasma gondii is Required for Infection: MS Proteome of Purified T. gondii Tachyzoites
Host nutrient acquisition is essential for apicomplexan parasite infection, yet mechanisms underpinning this are not defined. We discovered the genome of Toxoplasma gondii lacks conserved genes for iron transport and storage and show these host cell proteins including the transferrin receptor 1, tra...
ORGANISM(S): Homo sapiens (Human) Toxoplasma gondii Toxoplasma gondii RH 
2026-10-01 | PXD084269 | Pride
Human Mrc5 Theft T. gondii Toxoplasma gondii Iron Toxoplasma 
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