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Epitranscriptomic RNA modifications can regulate fundamental biological processes, but we lack approaches to map modification sites and probe writer enzymes. Here we present a chemoproteomic strategy to characterize RNA 5-methylcytidine (m5C) dioxygenase enzymes in their native context based upon me...
ORGANISM(S): Homo sapiens (Human) 
2022-07-16 | PXD029955 | Pride
Reactivity-dependent profiling of RNA 5-methylcytidine dioxygenases
Reactivity-dependent profiling of RNA 5-methylcytidine dioxygenases [II]
Reactivity-dependent profiling of RNA 5-methylcytidine dioxygenases [I]
The field of epitranscriptomics is growing in importance, with chemical modification of RNA being associated with a wide variety of biological phenomena. Mass spectrometry (MS) enables the identification of modified RNA residues within their sequence contexts, by using analogous approaches to shotgu...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-03-31 | PXD016308 | Pride
The field of epitranscriptomics is growing in importance, with chemical modification of RNA being associated with a wide variety of biological phenomena. Mass spectrometry (MS) enables the identification of modified RNA residues within their sequence contexts, by using analogous approaches to shotgu...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-12-31 | PXD012095 | Pride
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