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Diabetic nephropathy (DN) is a major cause of end-stage renal disease and has limited therapeutic options to prevent its progression. To identify novel therapeutic strategies, protective factors for DN were studied using proteomics on glomeruli from 50-year medalists (individuals with extreme durati...
ORGANISM(S): Homo sapiens (Human) 
2017-05-02 | PXD006339 | Pride
Gene expression analyses of fibroblasts obtained from healthy controls, Medalist -C patients and Medalist +C patients. Type 1diabetes (T1D) is associated with late complications, mechanisms underscoring which are poorly understood. We report the derivation of induced pluripotent stem cells (iPSCs) f...
ORGANISM(S): Homo sapiens 
2015-08-15 | GSE70752 | GEO
Preserved DNA Damage Checkpoint Pathway Protects From Complications in Long-standing Type 1 Diabetes
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