Sort   by:  
 Page size 
ProteomicsIdentification of Novel Auto-antibodies in Type 1 Diabetic Patients using a High-density Protein Microarray
Type 1 diabetes mellitus (T1DM) results from immune mediated destruction of pancreatic beta cells. However, clinical and immunologic phenotypes of T1DM are variable. Several auto-antibodies including GADA, IA-2A, and ZnT8A, were identified in T1DM, but the prevalence of these auto-antibodies varied ...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-50866 | biostudies-arrayexpress
ProteomicsMuSt multiomics
Multiomics of faecal samples collected from individuals in families with multiple cases of type 1 diabetes mellitus (T1DM) over 3 or 4 months. Metagenomic and metatranscriptomic sequencing and metaproteomics were carried out, as well as whole human genome sequencing. Phenotypic data is available.
ORGANISM(S): Mixed Culture Metagenome (ncbitaxon:1306859) 
2017-10-19 | MSV000081630 | MassIVE
UnknownPeptidome Analysis of Pancreatic Tissue Derived from T1DM Mice: Insights into the Pathogenesis and Clinical Treatments of T1DM.
Not available
S-EPMC8164536 | biostudies-literature
UnknownThe NLRP3 Inflammasome and Its Role in T1DM.
Not available
S-EPMC7481449 | biostudies-literature
UnknownLate-Onset T1DM and Older Age Predict Risk of Additional Autoimmune Disease.
Not available
S-EPMC6300704 | biostudies-literature
TranscriptomicsStreptozotocin-induced Type 1 and 2 Diabetes Mellitus Mouse Models Show Different Functional, Cellular and Molecular Patterns of Diabetic Cardiomyopathy
The main cause of morbidity and mortality in diabetes mellitus (DM) are cardiovascular complications. Diabetic cardiomyopathy (DCM) remains incompletely understood. Animal models have been crucial in exploring DCM pathophysiology while identifying potential therapeutic targets. Streptozotocin (STZ) ...
ORGANISM(S): Mus musculus 
2023-02-20 | E-MTAB-12558 | biostudies-arrayexpress
ProteomicsPharmacological activation of LRH-1/NR5A2 triggers an anti-inflammatory phenotypic switch in immune cells from individuals with type 1 diabetes and improves human islet engraftment/function
The intricate aetiology of type 1 diabetes mellitus (T1DM) implicating a detrimental cross talk between immune cells and insulin producing b-cells leading to their destruction has stumped the development of effective disease modifying therapies. The discovery that the pharmacological activation of L...
ORGANISM(S): Homo sapiens (Human) 
2025-04-09 | PXD053517 | Pride
T1dm Dendritic cells Proteomics 
ProteomicsCoordinated assembly of NHE3, IRBIT, NHERF1, and ezrin ameliorates fluid malabsorption in diabetes
Clinical evidence supports the occurrence of intermittent diarrhea in many type 1 diabetes mellitus (T1DM) patients. Others and we found that net fluid absorption rate is dramatically lower in the ileum of T1DM murine models. However, the identity of molecules that contribute to fluid malabsorption ...
ORGANISM(S): Mus musculus (Mouse) 
2016-04-27 | PXD001859 | Pride
Intestine Scaffold proteins Diabetes Brush border membrane Ion transporters 
UnknownCXCL12 as a Potential Hub Gene for N-Acetylcysteine Treatment of T1DM Liver Disease.
Not available
S-EPMC11853168 | biostudies-literature
UnknownNormoalbuminuric kidney impairment in patients with T1DM: insights from annals initiative.
Not available
S-EPMC6069993 | biostudies-literature
Sort   by:  
 Page size