A Jun J - OmicsDI

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Unknown (64459)
Proteomics (658)
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Metabolomics (297)
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Genomic (2)

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Mus musculus (210)
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Canis lupus familiaris (7)
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Organisms

Mus musculus (5)
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Repository

biostudies-arrayexpress (558)
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pride (281)
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geo (2)

Tissue

Cell culture (59)
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Breast (1)

Disease

Not Available (18)
Breast cancer (8)
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Wounds and Injuries (4)
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Aviremic HIV (1)
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TAC operated 1 hour after surgery (1)
Adenovirus infected (1)
Prostate cancer (1)
Invasive ductal carcinoma (1)
Alzheimer's disease (1)
Amyotrophic lateral sclerosis (1)

Technology Type

Mass Spectrometry (281)
Mass spectrometry (258)
Shotgun proteomics (181)
Affinity purification coupled with mass spectrometry proteomics (41)
Bottom-up proteomics (39)
NMR spectroscopy (30)
Gel-based experiment (22)
Mass spectrometry assay (11)
Data-dependent acquisition (11)
Fluorescence intensity (6)
SWATH MS (6)
Fluorescence imaging (5)
Chemical cross-linking coupled with mass spectrometry proteomics (5)
Top-down proteomics (5)
RPPA (4)
Data-independent acquisition (3)
SRM/MRM (3)
Illumina HiSeq 2500 (2)
Illumina HiSeq 2000 (2)
All-ion fragmentation (2)
HDMSE (2)
Mass spectrometry imaging (2)
Affymetrix/Illumina (1)
CAPILLARY, AB 3730xL Genetic Analyzer (1)
Illumina HiSeq 2500, Illumina MiSeq, NextSeq 500, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, Affymetrix SNP 6.0 (1)
Illumina HumanOmniExpress-12 v1., Illumina HiSeq 2000 (1)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
Illumina HumanExome-12v1_A-GenCall, zCall, GenoSNP, - Illuminus (1)
Glycoproteomics (1)

Instrument Platform

Q Exactive (25)
LTQ Orbitrap Velos (24)
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Instrument (18)
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Orbitrap Eclipse (3)
LTQ Orbitrap XL (3)
Illumina HiSeq 2000 (2)
NextSeq 500 (2)
Q Exactive HF (2)
TripleTOF 6600 (2)
LTQ Velos (2)
Orbitrap Exploris 480 (2)
Typhoon TRIO (1)
Illumina Genome Analyzer (1)
GenePix 4000B [Axon Instruments] (1)
Illumina Genome Analyzer II (1)
Scanning hardware (1)
NextSeq 2000 (1)
Illumina iSeq 100 (1)
LTQ Orbitrap (1)
LTQ Orbitrap Velos Pro (1)
LTQ XL (1)
NHMFL 21T FT-ICR-MS (1)

Publication Date

2022 (133)
2016 (117)
2023 (117)
2010 (116)
2021 (113)
2024 (105)
2013 (91)
2015 (90)
2014 (75)
2017 (69)
2020 (59)
2012 (58)
2011 (57)
2025 (45)
2019 (45)
2018 (45)
2008 (43)
2009 (30)
2026 (25)
2007 (20)
2005 (19)
2006 (6)
2004 (5)

UNIPROT ID/AC

P05132 (3)
Q3U214 (3)
P06213 (2)
Q9UUB7 (1)
Q5AFP3 (1)
Q22197 (1)
Q9Y2T1 (1)
Q06598 (1)
O14640 (1)
Q5EG47 (1)
P35569 (1)
P28700 (1)
P70284 (1)
Q64729 (1)
Q9WVS0 (1)
Q04683 (1)
Q9ES17 (1)
P18893 (1)
P07750 (1)
P04351 (1)
P42232 (1)
Q60636 (1)
P41183 (1)
P06332 (1)
Q8NES3 (1)
P35568 (1)
Q99JB6 (1)
Q05609 (1)
Q0WPQ2 (1)
P49333 (1)

ENSEMBL ID

ENSG00000170477 (12)
ENSG00000147251 (10)
ENSG00000247315 (10)
ENSG00000229353 (5)
ENSG00000139318 (1)
ENSG00000168646 (1)

CHEBI ID

CHEBI:15843 (37)
CHEBI:16761 (32)
CHEBI:15422 (28)
CHEBI:36080 (2)
CHEBI:16947 (2)
CHEBI:16452 (2)
CHEBI:15361 (2)
CHEBI:49172 (1)
CHEBI:16412 (1)
CHEBI:34159 (1)
CHEBI:18053 (1)
CHEBI:18153 (1)
CHEBI:23530 (1)
CHEBI:22676 (1)
CHEBI:29242 (1)
CHEBI:57597 (1)
CHEBI:16651 (1)
CHEBI:15589 (1)
CHEBI:55474 (1)
CHEBI:56080 (1)
CHEBI:61448 (1)
CHEBI:57604 (1)
CHEBI:58027 (1)
CHEBI:30616 (1)
CHEBI:27485 (1)
CHEBI:15554 (1)
CHEBI:15553 (1)
CHEBI:15555 (1)
CHEBI:57540 (1)
CHEBI:57945 (1)

Metabolite Name

Hypoxanthine (46)
Taurine (45)
Adenine (44)
Adenosine (43)
Uracil (41)
Creatine (41)
Creatinine (39)
Uridine (37)
L-Phenylalanine (37)
Glycine (35)
Xanthine (35)
L-Tyrosine (35)
Inosine (35)
Choline (33)
L-Glutamine (31)
L-Leucine (31)
L-Proline (30)
L-Arginine (30)
L-Histidine (30)
Guanosine (30)
Citric acid (29)
Uric acid (29)
Ornithine (28)
L-Tryptophan (28)
Tryptophan (28)
L-Isoleucine (28)
L-Methionine (28)
Valine (27)
Betaine (27)
L-Lysine (27)

First Public Date

2014 (5)
2025 (2)
2026 (1)
2020 (1)
2016 (1)
2015 (1)

Modelling Approach

Ordinary differential equation model (41)
Constraint-based model (5)

Lab affiliation

CEA-Marcoule, DSV-iBEB-SBTN-LBSP, 30207 Bagnols-sur-Cèze, France (4)
Medical Research Council Mitochondrial Biology Unit, University of Cambridge. U.K. (4)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (3)
Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo (3)
Professor Institutt for kreftforskning og molekylær medisin Erling Skjalgssons g 1, Laboratoriesenteret * 231.05.036 Trondheim 7030, Norway (3)
University at buffalo, SUNY (3)
1. Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, UK 2. Department of Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, Germany (2)
BMI, Faculty of Medicine, University of Ottawa, Canada (2)
CEA, DSV, IBiTec-S, SPI, Li2D, Laboratory "Innovative technologies for Detection and Diagnostics", Bagnols-sur-Cèze, F-30200, France (2)
Department of Chemistry and Biochemistry. University of Colorado, Boulder. Boulder, CO 80303 (2)
Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA (2)
Department of Gene Regulation Friedrich Miescher Institutefor Biomedical Research (2)
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland (2)
Global Health Institute, EPFL, Lausanne, Switzerland (2)
Institute of Reproductive Medicine, Medical School, Nantong University, Nantong 226001, China (2)
NARO Institute of Crop Science (2)
Northwest University (2)
Pacific Northwest National Laboratory, USA (2)
School of Life Science and Technology ShanghaiTech University 100 Haike Road, Shanghai, China (2)
Shenzhen People’s Hospital (2)
University Hospital Cologne (2)
.Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; (1)
1. Istitituto Sperimentale Italiano L. Spallanzani,Milano, Italy; 2. Dipartimento di Scienze Veterinarie e Sanità Pubblica, Università degli Studi di Milano, Milano, Italy. (1)
1: Department of Molecular Biology, Division of Chemistry andBioanalytics, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria 2: Christian Doppler Laboratory for Innovative Tools for Biosimilar Characterization, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria (1)
1Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (1)
Analytical Sciences (1)
Associate Professor, BMBB, University of Minnesota, Minneapolis, MN (1)
BMBB, University of Minnesota, USA (1)
Baker Heart & Diabetes Institute (1)
Basic Sciences, College of Veterinary Medicine (1)

IsPrivate

False (48)

Model Flag

Non Kinetic (7)
Non Miriam (1)

Submitter Keywords

TransQST (1)

Modification

57.021464 (4)
-17.026549 (3)
42.010565 (3)
-18.010565 (2)
15.994915 (2)
4x(15)N labeled L-arginine (2)
N6 (2)
Not available (2)
+3amu) (1)
15.99491 (1)
2x(15)N labeled L-lysine (1)
57.02146 (1)
71.037114 (1)

Study type

Transcription profiling by array (319)
RNA-seq of coding RNA (75)
Unknown experiment type (44)
ChIP-seq (34)
Transcription profiling by tiling array (16)
RNA-seq of non coding RNA (15)
ChIP-chip by tiling array (12)
Other (5)
MicroRNA profiling by array (5)
Methylation profiling by array (5)
Transcription profiling by SAGE (4)
Comparative genomic hybridization by array (4)
ChIP-chip by array (3)
Transcription profiling by RT-PCR (3)
Methylation profiling by high throughput sequencing (3)
Genotyping by array (2)
One-color microarray (1)
Cell line - One-color microarray (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
RNAi profiling by array (1)
Bisulfite-seq (1)
ATAC-seq (1)
DNA-seq (1)

Release Date

2022 (9027)
2021 (7746)
2023 (7611)
2020 (5875)
2024 (4676)
2019 (4372)
2025 (4338)
2018 (3698)
2017 (3268)
2016 (2889)
2015 (2267)
2014 (1945)
2013 (1184)
2012 (1111)
2010 (1025)
2011 (999)
2009 (743)
2008 (551)
2007 (394)
2006 (308)
2005 (208)
2026 (138)
2004 (131)
2003 (118)
2002 (103)
2001 (94)
2000 (86)
1999 (53)
1998 (36)
1997 (13)

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Overexpression of c-Jun in mouse Schwann cells of uninjured nerves

Two mouse lines, OE/+ and OE/OE were generated expressing graded elevation (6 fold and 28 fold, respectively) of c-Jun protein selectively in Schwann cells. The effects of this on global gene expression and cellular structure in uninjured nerves was analysed during development and in the adult. Chan...

ORGANISM(S): Mus musculus

2017-10-16 | E-MTAB-6138 | biostudies-arrayexpress

c-JUN interacte with NuRD complex to regulate chromatin remodeling

detect c-JUN interaction proteins in humanembryonic stem cells

ORGANISM(S): Homo Sapiens

2023-12-28 | PXD048153 |

CHIP Analysis - c-Jun/ATF2

Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress

ORGANISM(S): Homo sapiens

2010-06-05 | E-GEOD-1810 | biostudies-arrayexpress

Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during the chronic denervation that results from slow axon growth. This impairs axonal regeneration and ca...

ORGANISM(S): Mus musculus

2020-10-14 | E-MTAB-9640 | biostudies-arrayexpress

The AP-1 Transcription Factor c-Jun Prevents Stress-Imposed Maladaptive Remodeling of the Heart

Systemic hypertension increases cardiac workload and subsequently induces signaling networks in heart that underlie myocyte growth (hypertrophic response) through expansion of sarcomeres with the aim to increase contractility. However, conditions of increased workload can induce both adaptive and ma...

ORGANISM(S): Mus musculus

2013-09-19 | E-GEOD-47898 | biostudies-arrayexpress

A chromatin-modifying function of JNK during stem cell differentiation

Signaling mediates cellular responses to extracellular stimuli. The c-Jun NH2-terminal kinase (JNK) pathway exemplifies one sub-group of Mitogen-activated protein (MAP) kinases, which besides established functions in stress response, also contributes to developmental processes by an unknown mechanis...

ORGANISM(S): Mus musculus

2011-12-18 | E-GEOD-25532 | biostudies-arrayexpress

PRR7 is a novel NMDA-dependent inhibitor of c-Jun ubiquitination in neurons

Elevated c-Jun levels result in apoptosis and are evident in neurodegenerative disorders such as Alzheimer's disease and dementia and after global cerebral insults such as stroke and epilepsy. NMDA receptor (NMDAR) antagonists block c-Jun upregulation and prevent neuronal cell death following excito...

ORGANISM(S): Rattus norvegicus

2014-10-25 | E-GEOD-62686 | biostudies-arrayexpress

microRNA Profiling in Wilms Tumors and Kidney Tissues

The IGF2-intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis. The expression levels of microRNAs were profiled in 20 human Wilms tumor samples (WT), 3 human normal adult kidney samples (AK) and 5 human fetal kidney samples (FK) using a Luminex bea...

ORGANISM(S): Homo sapiens

2013-12-22 | E-GEOD-50505 | biostudies-arrayexpress

In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS769 | MetaboLights

Transcription profiling of hematopoietic stem cells in the preleukemic phase from wiltype mice and mice deficient in transcription factor PU.1 to identify transcriptional changes preceding malignant transformation

Knockdown of the transcription factor PU.1 (Spi1) leads to acute myeloid leukemia (AML) in mice. We examined the transcriptome of PU.1 knockdown hematopoietic stem cells (HSC) in the preleukemic phase by linear amplification and genome-wide array analysis to identify transcriptional changes precedin...

ORGANISM(S): Mus musculus

2007-11-22 | E-GEOD-5654 | biostudies-arrayexpress

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