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ProteomicsIdentification of immune-based biomarkers associated with response to abatacept (CTLA4-Ig) in rheumatoid arthritis patients.
RA patients (according to ACR/EULAR 2010 criteria) who started abatacept due to high disease activity (DAS28>5.1), were recruited to perform immunological studies at baseline, 3 and 6 months of therapy. Peripheral blood mononuclear cells (PBMCs) were isolated and immune cell populations were charact...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046112 | Pride
Abatacept Th1 Ctla4-ig Immune cells Biomarkers Rheumatoid arthritis Secretome 
GenomicsRheumatoid arthritis synovium response to abatacept
Rheumatoid arthritis synovium response to abatacept
PRJNA722354 | ENA
UnknownEffect of abatacept on immunogenicity of vaccines in individuals with type 1 diabetes.
Not available
S-EPMC3803163 | biostudies-literature
GenomicsRNA_seq analysis on Tfh and Treg before and after abatacept treatment
RNA_seq analysis on Tfh and Treg before and after abatacept treatment
PRJNA498531 | ENA
GenomicsGene expression profiles of peripheral blood mononuclear cells before abatacept treatment in rheumatoid arthritis patients.
Gene expression profiles of peripheral blood mononuclear cells before abatacept treatment in rheumatoid arthritis patients.
PRJNA932776 | ENA
GenomicsA Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis (ASSET)
A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis (ASSET)
PRJNA1098875 | ENA
GenomicsA Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis (ASSET)
A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis (ASSET)
PRJNA1098874 | ENA
GenomicsAbatacept Restores Dysregulated Transcriptomic and Proteomic Profiling in LRBA Deficiency and CTLA-4 Insufficiency
Abatacept Restores Dysregulated Transcriptomic and Proteomic Profiling in LRBA Deficiency and CTLA-4 Insufficiency
PRJNA1261703 | ENA
TranscriptomicsGene expression profiles of peripheral blood mononuclear cells before abatacept treatment in rheumatoid arthritis patients.
To explore markers which predict the efficacy of abatacept in rheumatoid arthritis, peripheral blood mononuclear cells were obtained before abatacept treatment.
ORGANISM(S): Homo sapiens 
2023-04-10 | GSE224842 | GEO
GenomicsB lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes
B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes
PRJNA511467 | ENA
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