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TranscriptomicsMicroarray-based comparative genomic profiling of reference strains of Actinobacillus pleuropneumoniae
Microarray-based comparative genomic hybridizations were used to estimate whole genomic diversity of representative Actinobacillus pleuropneumoniae strains. Our goal was to identify conserved genes, especially those predicted to encode outer membrane proteins and lipoproteins because of their potent...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2009-02-02 | E-GEOD-11921 | biostudies-arrayexpress
TranscriptomicsExpression data of Actinobacillus pleuropneumoniae 4074 and the M-NM-^TluxS mutant of Actinobacillus pleuropneumoniae 4074
LuxS is an enzyme involved in the activated methyl cycle and the by-product autoinducer 2 (AI-2) was a quorum sensing signal in some species. In our previous study, the functional LuxS in AI-2 production was verified in the porcine respiratory pathogen Actinobacillus pleuropneumoniae. Enhanced biofi...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2011-11-09 | E-GEOD-19056 | biostudies-arrayexpress
TranscriptomicsGenome wide transcriptional portrait of Actinobacillus pleuropneumoniae during invasive disease reveals new strategies for survival and persistence in the host
The transcriptional profile of the porcine lung pathogen, Actinobacillus pleuropneumoniae, was monitored during the acute phase of infection in its natural host. Bacterial expression profiles of A. pleuropneumoniae isolated from lung lesions of 25 infected pigs were compared in samples taken 6, 12, ...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2012-12-01 | E-GEOD-33999 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Actinobacillus pleuropneumoniae wild type, hns mutants and rseA mutants
Clinical isolates of the porcine pathogen Actinobacillus pleuropneumoniae often form adherent colonies on agar plates due to expression of an operon, pgaABCD, encoding a poly-N-acetylglucosamine (PGA) extracellular matrix. The adherent colony phenotype, which correlates with the ability to form a bi...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2010-04-22 | E-MEXP-2461 | biostudies-arrayexpress
TranscriptomicsComparative genomic profiling of reference strains and selected Canadian field isolates of A. pleuropneumoniae
Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is a highly contagious respiratory pathogen that causes severe losses to the swine industry worldwide. Current commercially-available vaccines are of limited value because they do not induce cross-serovar immunity and d...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2009-01-30 | E-GEOD-14639 | biostudies-arrayexpress
TranscriptomicsTranscript profiling in Actinobacillus pleuropneumoniae after adherence to, or planktonic growth over, SJPL cells.
Host-pathogen interactions are of great importance in understanding the pathogenesis of infectious microorganisms. We developed in vitro models to study porcine respiratory tract pathogens using an immortalized epithelial cell line, the St. Jude Porcine Lung (SJPL) cell line. In conditions where cy...
ORGANISM(S): Actinobacillus pleuropneumoniae 
2008-07-09 | E-GEOD-12009 | biostudies-arrayexpress
GenomicsActinobacillus pleuropneumoniae
Actinobacillus pleuropneumoniae Genome sequencing
PRJNA922050 | ENA
ProteomicsActinobacillus pleuropneumoniae serotype 2 exoproteome LF-LC-MS/MS
Porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae affects pig health status and the swine industry worldwide. Despite of the extensive number of studies focused on A. pleuropneumoniae infection and vaccine development, its exoproteome is still rather unexplored. By combining high-thr...
ORGANISM(S): Actinobacillus pleuropneumoniae serovar 2 
2022-10-13 | PXD029396 | Pride
Porcine pleuropneumonia Exoproteome Actinobacillus pleuropneumoniae 
ProteomicsSWATH-MS proteome of Actinobacillus pleuropneumoniae showing differential protein expression due to the ModP and ModQ phasevarions
Actinobacillus pleuropneumoniae is responsible for porcine pleuropneumoniae, a severe respiratory disease that causes major global financial losses to the swine industry every year. Phase variation is the random switching of gene expression, either ON-OFF switching of expression, or the expression o...
ORGANISM(S): Actinobacillus pleuropneumoniae serovar 7 str. AP76 Actinobacillus pleuropneumoniae serovar 3 str. JL03 
2023-05-10 | PXD036273 | Pride
Phasevarions Epigenetics Bacteria Actinobacillus pleuropneumoniae Methyltransferase 
GenomicsActinobacillus pleuropneumoniae
Actinobacillus pleuropneumoniae Assembly
PRJNA1122341 | ENA
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