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TranscriptomicsInvestigation of the Molecular Action of Actinorhodin
Actinorhodin is a blue-pigmented, redox-active pigmented secondary metabolite that is produced by the bacterium Streptomyces coelicolor. Although actinorhodin has been used as a model compound for studying secondary metabolism, its mechanism is not well understood. In this work, we have conducted a ...
ORGANISM(S): Staphylococcus aureus 
2017-09-21 | GSE97007 | GEO
ProteomicsThe small ORF trpM stimulates growth and actinorhodin production in Streptomyces coelicolor
In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many others still deserve further investigations...
ORGANISM(S): Streptomyces coelicolor 
2020-03-27 | PXD015937 | Pride
Streptomyces coelicolor Primary and secondary metabolism Calcium-dependent antibiotic (cda) Actinorhodin production Cytosol aminopeptidase Small orf 
GenomicsEvidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145
CutRS was the first two-component system to be identified in Streptomyces species and is highly conserved in this genus. It was reported >25 years ago that deletion of cutRS increases the production of the antibiotic actinorhodin in Streptomyces coelicolor but despite this early work the function of...
ORGANISM(S): Streptomyces coelicolor 
2023-06-12 | GSE225370 | GEO
TranscriptomicsTranscription profiling of Streptomyces coelicolor wild type and delta0877 and delta7173 mutant strains
Gene expression analysis of S. coelicolor M145 wild type strain, and mutants delta0877 and delta 7173. RNA samples were extracted from 48 h culture samples during growth in flasks in defined mineral medium MG supplemented with 5% of yeast extract. Cy5 labelled genomic DNA was used as the common ref...
ORGANISM(S): Streptomyces coelicolor 
2009-04-17 | E-MEXP-2132 | biostudies-arrayexpress
GenomicsTime-course transcriptome analysis of non-antibiotics producer and actinorhodin over-producing Streptomyces coelicolor strain
Time-course transcriptome analysis of non-antibiotics producer and actinorhodin over-producing Streptomyces coelicolor strain
PRJNA655669 | ENA
GenomicsStaphylococcus aureus
Investigation of the Molecular Action of Actinorhodin
PRJNA380398 | ENA
GenomicsEvidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145
Evidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145
PRJNA935355 | ENA
TranscriptomicsTranscription profiling by array of Streptomyces coelicolor actinorhodin-producing wild type andrecombinant strains
Genome-wide expression analysis of 6 batch cultivations of actinorhodin-producing wild type and recombinant strain of Streptomyces coelicolor
ORGANISM(S): Streptomyces coelicolor A3(2) 
2010-05-25 | E-MTAB-306 | biostudies-arrayexpress
UnknownA two-step mechanism for the activation of actinorhodin export and resistance in Streptomyces coelicolor.
Not available
S-EPMC3482498 | biostudies-literature
UnknownSynthetic promoter library for modulation of actinorhodin production in Streptomyces coelicolor A3(2).
Not available
S-EPMC4070896 | biostudies-literature
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