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ProteomicsThe small ORF trpM stimulates growth and actinorhodin production in Streptomyces coelicolor
In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many others still deserve further investigations...
ORGANISM(S): Streptomyces coelicolor 
2020-03-27 | PXD015937 | Pride
Streptomyces coelicolor Primary and secondary metabolism Calcium-dependent antibiotic (cda) Actinorhodin production Cytosol aminopeptidase Small orf 
UnknownGenome-Wide Mutagenesis Links Multiple Metabolic Pathways with Actinorhodin Production in Streptomyces coelicolor.
Not available
S-EPMC6585502 | biostudies-literature
UnknownSynthetic promoter library for modulation of actinorhodin production in Streptomyces coelicolor A3(2).
Not available
S-EPMC4070896 | biostudies-literature
GenomicsEvidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145
CutRS was the first two-component system to be identified in Streptomyces species and is highly conserved in this genus. It was reported >25 years ago that deletion of cutRS increases the production of the antibiotic actinorhodin in Streptomyces coelicolor but despite this early work the function of...
ORGANISM(S): Streptomyces coelicolor 
2023-06-12 | GSE225370 | GEO
TranscriptomicsThe immediate effect of high-intensity green LED stimulation on the gene expression profile of S. coelicolor A3(2)
We investigated a novel, simple approach to induce the production of cryptic secondary metabolites in actinomycetes by stimulating the organism with high-intensity monochromatic green light (180 radiation unit). Streptomyces coelicolor A3(2) produces blue antibiotic actinorhodin (ACT) and red antibi...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2023-12-10 | E-MTAB-12876 | biostudies-arrayexpress
UnknownExpression of the Streptomyces coelicolor SoxR regulon is intimately linked with actinorhodin production.
Not available
S-EPMC3008532 | biostudies-literature
UnknownSulfane sulfur-activated actinorhodin production and sporulation is maintained by a natural gene circuit in Streptomyces coelicolor.
Not available
S-EPMC7533328 | biostudies-literature
UnknownThe SCO1731 methyltransferase modulates actinorhodin production and morphological differentiation of Streptomyces coelicolor A3(2).
Not available
S-EPMC6135851 | biostudies-literature
UnknownAn additional regulatory gene for actinorhodin production in Streptomyces lividans involves a LysR-type transcriptional regulator.
Not available
S-EPMC93938 | biostudies-literature
UnknownMulti-Omics Analysis of the Effect of cAMP on Actinorhodin Production in Streptomyces coelicolor.
Not available
S-EPMC7674942 | biostudies-literature
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