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ProteomicsTandem mass tag-based proteomic analysis in saliva of horses with acute abdominal disease
The objective of the study was to analyze the changes in proteomics that occur in saliva in acute abdominal disease (AAD) by proteomics in order to identify new proteins that could allow gaining knowledge about the physiopathological changes that can occur in this fluid and identify possible new bio...
ORGANISM(S): Equus caballus (Horse) 
2021-05-24 | PXD025241 | Pride
Proteomics Tmt Horse Saliva Acute abdominal disease 
MetabolomicsMetabolomic analyses in sepsis-associated acute lung injury rats

Sepsis-associated acute lung injury (SALI) is a life-threatening pulmonary complication triggered by sepsis, which carries a notably high mortality rate. We constructed a rat model of SALI and administered Xuanbai Chengqi Decoction (XCD) as treatment, after which untargeted serum metabolomics ana...

2026-09-29 | MTBLS15292 | MetaboLights
TranscriptomicsRole of ICOS:ICOSL interaction in acute GVHD
Inducible co-stimulator (ICOS) interaction with its ligand (ICOSL) is involved in several T cell effector functions. While blockade of ICOS:ICOSL interaction in chronic graft versus host disease (GVHD) seems benefi cial, results for acute GVHD remain controversial. To further elucidate its role in a...
ORGANISM(S): Mus musculus 
2009-09-14 | E-GEOD-17995 | biostudies-arrayexpress
ProteomicsDiscovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease - 2nd cohort
In order to identify differentially abundant proteins, human plasma samples from COVID-19 patients with either a mild or moderate (MM) or a critical or severe (CS) disease course from acute phase of infection were analyzed on antibody microarrays 998 different proteins by 1,425 antibodies.
ORGANISM(S): Homo sapiens 
2023-03-15 | E-MTAB-12777 | biostudies-arrayexpress
ProteomicsDiscovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease - 1st cohort
In order to identify differentially abundant proteins, human plasma samples from COVID-19 patients with either a mild or moderate (MM) or a critical or severe (CS) disease course from the acute phases of infection were analyzed on antibody microarrays targeting 351 different proteins by 517 antibodi...
ORGANISM(S): Homo sapiens 
2023-04-11 | E-MTAB-12779 | biostudies-arrayexpress
TranscriptomicsHepatic transcriptional profiling of juvenile broiler chickens divergently selected for abdominal fatness or leanness
Chickens divergently selected for either high abdominal fat content (fat genotype) or low abdominal fat content (lean genotype) at SRA-INRA, France were used to profile hepatic gene expression during juvenile development (1 to 11 weeks of age) and to identify differentially expressed genes associate...
ORGANISM(S): Gallus gallus 
2007-08-31 | E-GEOD-8812 | biostudies-arrayexpress
ProteomicsProfiling Tryptophan Catabolites of Human Gut Microbiota and Acute-Phase Protein Levels in Neonatal Dried Blood Specimens
National screening programs use dried blood specimens to detect abnormal metabolism or aberrant protein function in infants shortly after birth, thus identifying disorders that are not clinically evident in the newborn period. Gut microbiota metabolites and immunological acute phase proteins are cap...
ORGANISM(S): Homo Sapiens 
2022-08-02 | PXD027606 | panorama
TranscriptomicsSpecificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection
Pathogenic mycobacteria have the ability to survive within macrophages and persist inside granulomas composed of host immune cells. The complex host-pathogen interactions that determine the outcome of a mycobacterial infection process result in marked alterations of the host gene expression profile....
ORGANISM(S): Danio rerio 
2010-05-15 | E-GEOD-15328 | biostudies-arrayexpress
TranscriptomicsAcute Lymphocytic Leukemia versus associated xenografts
Leukemic cells from either peripheral blood or bone marrow were obtained from 6 patients with acute lymphocytic leukemia. These cells were used to generate mouse xenografts and a comparison was made between those two sample sources. Six pairs of human leukemia and associated xenografts are compared...
ORGANISM(S): Homo sapiens 
2010-10-18 | E-GEOD-15621 | biostudies-arrayexpress
GenomicsGenome-wide analysis of Estrogen Receptor-mediated response to acute Estradiol treatment in liver (ChIP-seq)
Estrogen-based treatments have numerous extra-reproductive effects. On the one hand, they have protective metabolic actions against abdominal fat accumulation, type 2 diabetes, liver steatosis,… But, on the other hand, the oral route of administration, presumably due to a hepatic impact on liver-d...
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-70346 | biostudies-arrayexpress
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