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UnknownMice Lacking RIP3 Kinase are not Protected from Acute Radiation Syndrome.
Not available
S-EPMC6020684 | biostudies-literature
TranscriptomicsHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Severe acute respiratory syndrome coronavirus (SARS-CoV) causes a respiratory disease leading to death in 10% of the infected people. A mouse adapted SARS-CoV lacking the envelope (E) protein (rSARS-CoV-MA15-?E) is attenuated in vivo. To identify E protein domains and host responses that contribute ...
ORGANISM(S): Mus musculus 
2015-05-19 | E-GEOD-59185 | biostudies-arrayexpress
MetabolomicsTargeted LC-MS analysis for lipidomics of mice intestinal samples

Mice of C57BL/6 were received a single dose of 12 Gy of the whole abdominal radiation (WART) to establish acute radiation bowel injury model. Approximately 12 hours post-irradiation, mice were orally administrated with PBS, DY802 and TG-CS@DY802 respectively. For 5 days consecutive treatment...

2026-04-02 | MTBLS14210 | MetaboLights
TranscriptomicsTranscription profiling of human lymphoblastoid cells from patients with limited or acute radiation toxicity, skin cancer patients and normal controls, exposed to UV or IR light
Peripheral blood lymphocytes from a total of 57 patients were immortalized with Epstein-Barr virus. Fourteen radiation-therapy patients suffered unusual levels of radiation toxicity (RadS). Thirteen radiation-therapy patients with limited toxicity (RadC) were enrolled as controls. Fifteen patient...
ORGANISM(S): Homo sapiens 
2007-08-05 | E-GEOD-1725 | biostudies-arrayexpress
ProteomicsLC-MS/MS EThcD of MERS-CoV and SARS-CoV S N-linked glycopeptides from recombinant spike ectodomains and whole MERS virions
Recent outbreaks of severe acute respiratory syndrome and Middle-East respiratory syndrome along with the threat of a future coronavirus pandemic underscore the importance of finding ways to neutralize these viruses. The trimeric spike transmembrane glycoprotein S mediates entry into host cells and ...
ORGANISM(S): Severe Acute Respiratory Syndrome-related Coronavirus (ncbitaxon:694009) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626) 
2020-03-13 | MSV000085097 | MassIVE
UnknownIEPA, a novel radiation countermeasure, alleviates acute radiation syndrome in rodents.
Not available
S-EPMC11698650 | biostudies-literature
TranscriptomicsNon-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy), 1 and 4 weeks after exposure. Gene expression that is modified under these parameters were compared between Tgfb1 wild type and heterozygote li...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-18216 | biostudies-arrayexpress
UnknownActivation of Angiotensin-Converting Enzyme 2 Mitigates Gastrointestinal Acute Radiation Syndrome.
Not available
S-EPMC12797870 | biostudies-literature
TranscriptomicsIntegrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia
Background: MicroRNAs are regulators of gene expression, mainly functioning by decreasing mRNA levels of their multiple targets. Deregulated microRNA expression has been shown for acute myeloid leukemia, a disease also characterized by altered gene expression associated with distinct genomic aberrat...
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31644 | biostudies-arrayexpress
TranscriptomicsMicroarray profiles of radiation response in the NCI60 cell lines
The 60 cell lines of the NCI Anti-Cancer Drug Screen (NCI60) constitute the most extensively characterized in vitro cancer cell model, and have been tested for sensitivity to over 100,000 potential chemotherapy agents. We have used the NCI60 cell lines and three additional lymphoblast lines to deve...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-7505 | biostudies-arrayexpress
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